| Mdpi AG

189,200원  | 20190618  | 9783039210602

The mechanistic target of rapamycin (mTOR) is a major signaling intermediary that coordinates favorable environmental conditions with cell growth. Indeed, as part of two functionally distinct protein complexes, named mTORC1 and mTORC2, mTOR regulates a variety of cellular processes, including protein, lipid, and nucleotide synthesis, as well as autophagy.

Pelton, Ross  | Hunter Lewis Foundation

19,470원  | 20230626  | 9781607660170

 | Mdpi AG

112,780원  | 20201203  | 9783039435531

The mechanistic/mammalian target of rapamycin (mTOR), a serine/threonine kinase, is a central regulator for human physiological activity. Deregulated mTOR signaling is implicated in a variety of disorders, such as cancer, obesity, diabetes, and neurodegenerative diseases.

 | Springer Nature B.V.

70,480원  | 20160616  | 9783319342108

In the post human-genome project era, cancer specific genomic maps are redesigning?tumor taxonomy by evolving from histopathology to molecular pathology. The success of a cancer drug today is fundamentally based on the success in identifying target genes that control?beneficial pathways.

Polunovsky, Vitaly  | Springer

387,730원  | 20210101  | 9781603272704

mTOR Pathway and mTOR Inhibitors in Cancer Therapy provides an up-to-date survey of the rapidly advancing field of cancer therapy. Our understanding of the mechanisms involved in cancer genesis and progression underwent unprecedented expansion during the last decade, opening a new era of cancer treatment - targeted therapy. The surge in this area results in no small part from studies conducted jointly by basic health scientists and clinical investigators.