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· 분류 : 외국도서 > 과학/수학/생태 > 과학 > 생명과학 > 생물학
· ISBN : 9780123745460
· 쪽수 : 1036쪽
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Part I. Microbial glycolipids, glyoproteins and glycopolymers? 1. Overview of the glycosylated components of the bacterial cell wall?? 2. Bacterial cell wall envelope peptidoglycan?? 3. Core oligosaccharide and lipid A components of lipopolysaccharides?? 4. O-Specific polysaccharides of Gram-negative bacteria?? 5. Teichoic acids, lipoteichoic acids, and related cell wall glycopolymers of Gram-positive bacteria?? 6. Bacterial capsular polysaccharides and exopolysaccharides?? 7. Bacterial surface layer glycoproteins and “non-classical? secondary cell wall polymers?? 8. Glycosylation of bacterial and archaeal flagellins?? 9. Glycosylated components of the mycobacterial cell wall: structure and function?? 10. Glycoconjugate structure and function in fungal cell walls?? 11. Cytoplasmic carbohydrate molecules: trehalose and glycogen?? 12. Glycosylated compounds of parasitic protozoa?? 13. Analytical approaches towards the structural characterization of microbial wall glycopolymers?? 14. Single-molecule characterization of microbial polysaccharides?? 15. Viral surface glycoproteins in carbohydrate recognition: structure and modeling?Part II. Synthesis of microbial glycosylated components; A. Biosynthesis and biosynthetic processes? 16. Biosynthesis of bacterial peptidoglycan?? 17. Biosynthesis and membrane assembly of lipid A?? 18. Biosynthesis of O-antigen chains and assembly?? 19. Biosynthesis of cell wall teichoic acid polymers?? 20. Biosynthesis and assembly of capsular polysaccharides?? 21. Biosynthesis of the mycobacterial cell envelope components?? 22. Biosynthesis of fungal and yeast glycans?B. Chemical synthesis?? 23. Chemical synthesis of bacterial lipid A?? 24. Chemical synthesis of the core oligosaccharide of bacterial lipopolysaccharide?? 25. Chemical synthesis of lipoichoic acid and derivatives?? 26. Chemical synthesis of parasitic glycoconjugates and phosphoglycans? Part III. Microbe-host glycosylated interactions?? 27. Bacterial lectin-like interactions in cell recognition and adhesion?? 28. Lectin-like interactions in virus-cell recognition: human immunodeficiency virus and C-type lectin interactions?? 29. Sialic acid-specific microbial lectins??? 30. Bacterial toxins and their carbohydrate receptors at the host-pathogen interface?? 31. Toll-like receptor recognition of lipoglycans, glycolipids and lipopeptides?? 32. NOD receptor recognition of peptidoglycan?? 33. Microbial interaction with mucus and mucins?? 34. Mannose-fucose recognition by DC-SIGN?? 35. Host surfactant proteins in microbial recognition?? 36. T-cell recognition of microbial lipoglycans and glycolipids? Part IV. Biological relevance of microbial glycosylated components; A. Environmental relevance?? 37. Extracellular polymeric substances in microbial biofilms?? 38. Physico-chemical properties of microbial glycopolymers?? 39. Microbial biofilm-related polysaccharides in biofouling and corrosion?? 40. Microbial glycosylated components in plant disease??B. Medical relevance?? 41. Antigenic variation of microbial surface glycosylated molecules?? 42. Phase variation of bacterial surface glycosylated molecules in immune evasion?? 43. Molecular mimicry of host glycosylated structures by bacteria?? 44. Role of microbial glycosylation in host cell invasion? Part V. Biotechnological and medical applications?? 45. Exopolysaccharides produced by lactic acid bacteria in food and probiotic applications?? 46. Industrial exploitation by genetic engineering of bacterial glycosylation systems?? 47. Glycomimetics as inhibitors in anti-infection therapy?? 48. Bacterial polysaccharide vaccines: glycogonjugates and peptide-mimetics?? 49. Immunomodulation by zwitterionic polysaccharides?? 50. Future potential of glycomics in microbiology and infectious diseases?