Foundations of Regenerative Medicine (Hardcover)

Preface

I. INTRODUCTION TO REGENERATIVE MEDICINE Current and Future Perspectives of Regenerative medicine Fundamentals of cell-based therapies Stem Cell Research

II. BIOLOGIC AND MOLECULAR BASIS FOR REGENERATIVE MEDICINE Molecular Organization of Cells Cell-ECM interactions In Repair and Regeneration Developmental Mechanisms of Regeneration The molecular basis of pluripotency in Principles of Regenerative Medicine

III. CELLS AND TISSUE DEVELOPMENT Embryonic Stem Cells: Derivation and Properties Stem cells derived from amniotic fluid and placenta Bone Marrow stem cells: Properties and Pluripotency Mesenchymal Stem cells Islet Cell Therapy and Pancreatic Stem Cells Mechanical Determinants of Tissue Development Morphogenesis and Morphogenic Proteins Physical stress as a factor in tissue growth and remodeling Engineering Cellular Microenvironments Applications of Nanotechnology

IV. BIOMATERIALS FOR REGENERATIVE MEDICINE Design Principles in Biomaterials and Scaffolds Naturally Occurring Scaffold Materials Synthetic Polymers Surface Modification of Biomaterials Biocompatibility and Bioresponse to biomaterials

V. THERAPEUTIC APPLICATIONS: Cell Therapy Clinical islet transplantation Cell Based Repair for Cardiovascular Regeneration and Neovascularization Cell therapies for bone regeneration Cell-Based Therapies for Musculoskeletal Repair Hepatocyte Transplantation Cell Based Drug Delivery

VI. THERAPEUTIC APPLICATIONS: Tissue Therapy Engineering of Large Diameter Vessels Cardiac Tissue Intracorporeal Kidney Support Genitourinary System Tissue Engineering of the Reproductive System Phalanges and Small Joints Functional Tissue Engineering of Ligament and Tendon Injuries Skeletal Muscle Peripheral Nervous System Innovative Regenerative Medicine Approaches to Skin Cell Based Therapy for Patients With Burn Injuries

VII. REGULATION AND ETHICS Ethical Considerations To Make Is to Know: The Ethical Issues in Human Tissue Engineering Overview of FDA Regulatory Process Current Issues in US Patent Law