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· 분류 : 외국도서 > 의학 > 전염병
· ISBN : 9780123849397
· 쪽수 : 320쪽
목차
Chapter 1 Introduction
Viruses are Distinct from Living Organisms
The History of Virology
Living Host Systems
Cell Culture Methods
Serological/Immunological Methods
Ultrastructural Studies
‘Molecular Biology’
Further Reading
Chapter 2 Particles
The Function and Formation of Virus Particles
Capsid Symmetry and Virus Architecture
Helical capsids
Icosahedral (isometric) capsids
Enveloped Viruses
Complex Virus Structures
Protein-Nucleic Acid Interactions and Genome Packaging
Virus Receptors - Recognition and Binding
Other Interactions of the Virus Capsid with the Host Cell
Summary
Further Reading
Chapter 3 Genomes
The Structure and Complexity of Virus Genomes
Molecular Genetics
Virus Genetics
Virus Mutants
Types of mutant virus
Suppression
Genetic Interactions between Viruses
Non-genetic Interactions between Viruses
‘Large’ DNA Genomes
‘Small’ DNA Genomes
Positive-Strand RNA Viruses
Negative-Strand RNA Viruses
Segmented and Multipartite Virus Genomes
Reverse Transcription and Transposition
Evolution and Epidemiology
Summary
Further Reading
Chapter 4 Replication
Overview of Virus Replication
Investigation of Virus Replication
The Replication Cycle
Summary
Further Reading
Chapter 5 Expression
Expression of Genetic Information
Control of Prokaryote Gene Expression
Control of Expression in Bacteriophage e
Control of Eukaryote Gene Expression
Genome Coding Strategies
Transcriptional Control of Expression
Post-Transcriptional Control of Expression
Summary
Further Reading
Chapter 6 Infection
Virus Infections of Plants
Immune Responses to Virus Infections in Animals
Virus-Host Interactions
The Course of Virus Infections
Prevention and Therapy of Virus Infection
Virus Vectors and Gene Therapy
Chemotherapy of Virus Infections
Summary
Further Reading
Chapter 7 Pathogenesis
Mechanisms of Cellular Injury
Viruses and Immunodeficiency
Virus-Related Diseases
Bacteriophages and Human Disease
Cell Transformation by Viruses
Viruses and Cancer
New and Emergent Viruses
Zoonoses
Bioterrorism
Summary
Further Reading
Chapter 8 Subviral Agents: Genomes Without Viruses, Viruses Without Genomes
Satellites and Viroids
Prions
Summary
Further Reading
Appendix 1 Glossary and Abbreviations
Appendix 2 Classification of Subcellular Infectious Agents
Appendix 3 The History of Virology
Index
