Protein Kinase Inhibitors in Research and Medicine: Volume 548 (Hardcover)

1.?Catalytic Mechanisms and Regulation of Protein Kinases
Zhihong Wang and Philip A. Cole.
2.?A Structural Atlas of Kinases Inhibited by Clinically Approved Drugs
Qi Wang, Julie A. Zorn and John Kuriyan.
3.?Fragment-Based Approaches to the Discovery of Kinase Inhibitors
Paul N. Mortenson, Valerio Berdini and Marc O’Reilly.
4.?Targeting Protein Kinases with Selective and Semi-Promiscuous Covalent Inhibitors
Rand M. Miller and Jack Taunton.
5.?The Resistance Tetrad: Amino Acid Hotspots for Kinome-Wide Exploitation of Drug-resistant Protein Kinase Alleles
Veselin I Andreev and Patrick A Eyers
6.?FLiK: A Direct Binding Assay for the Identification and Kinetic Characterization of Stabilizers of Inactive Kinase Conformations
Jeffrey R. Simar and Daniel Rauh
7.?Discovery of Allosteric Bcr-Abl inhibitors from Phenotypic Screen to Clinical Candidate
Nathanael S. Gray and Doriano Fabbro
8.?The Logic and Design of Analog-Sensitive (AS) Kinases and their Small Molecule Inhibitors
Michael S. Lopez, Joseph Kliegman and Kevan M. Shokat