Introduction to Nuclear Mechanics and Genome Regulation (Paperback)

1. Physico-chemical constraints in DNA
2. 3D organization of chromosomes and functional gene clusters
3. Spatial dimension to DNA transcription, replication, damage and repair
4. Dynamics within the nucleus and functional microrheology
5. Cytoskeleton to nuclear links and prestressed nuclear architecture
6. Nuclear mechanotransduction and genetic networks
7. Chromatin plasticity during differentiation, development and reprogramming
8. Mechanical homeostasis of the nucleus during cell division and migration
9. Nuclear mechanics in diseases and as diagnostic markers
10. Evolutionary constraints in DNA packing and genome regulation