Spaceflight Associated Neuro-Ocular Syndrome (Paperback)

1. Definition of SANS
2. Clinical findings to date
3. Mechanisms of SANS
a. Cephalad fluid shift with intraorbital and intracranial volume increase
b. Increased intracranial pressure
c. Translaminar pressure gradient
d. Altered glymphatic drainage
e. Intracerebral volume and cerebral edema alterations
f. Orbital and cerebral arterial or venous drainage disturbance
g. One carbon pathway metabolism alterations
4. Optical coherence tomography and choroidal volume expansion
5. Hypercapnia related volume and pressure disturbances
6. Magnetic resonance imaging findings in SANS
7. Ultrasound findings in SANS
8. Long term follow up in SANS
9. Countermeasures for SANS
10. Screening for SANS
11. Future directions