Basic Clinical Radiobiology Fourth Edition (Hardcover, 4 New edition)

1.Introduction: the significance of radiobiology and radiotherapy for cancer treatment
2. Irradiation-induced damage and the DNA damage response
3. Cell death after irradiation: how, when and why cells die
4. Quantitating cell kill and cell survival
5. Models of radiation response
5. Dose-response relationships in radiotherapy
6. LET and RBE
7. Tumour growth and response to radiation
8. Fractionation: the L-Q approach
9. The L-Q approach in clinical practice
10. Modified fractionation
11. Time factors in normal-tissue response to radiation
12. The dose-rate effect
13. Pathogenesis of normal-tissue side-effects
14. The volume effect in radiotherapy
15. The oxygen effect and fractionated radiotherapy
16. The tumour microenvironment and cellular hypoxia responses
17. Therapeutic approaches to tumor hypoxia
18. Combined radiotherapy and chemotherapy
19. Retreatment tolerance of normal tissues
20.Molecular image-guided radiotherapy with positron emission tomography
21. Molecular-targeted agents for enhancing tumour response
22. Biological response modifiers in the clinic: tumor
22. Biological response modifiers: normal tissue
23. Molecular targeting and patient individualization
24.Protons and other ions in radiotherapy
25. Second cancers after radiotherapy