Cancer Clinical Trials : Current and Controversial Issues in Design and Analysis (Paperback)

General Issues Endpoints for Cancer Clinical Trials Stephen L. George, Xiaofei Wang, and Herbert Pang Use of Historical Data Simon Wandel, Heinz Schmidli, and Beat Neuenschwander Multiplicity Dong Xi, Ekkehard Glimm, and Frank Bretz Analysis of Safety Data Steven Snapinn and Qi Jiang Early Phase Clinical Trials Development and Validation of Predictive Signatures Michael C. Sachs and Lisa M. McShane Phase I Trials and Dose-Finding Mark R. Conaway and Nolan A. Wages Design and Analysis of Phase II Cancer Clinical Trials Sin-Ho Jung Late Phase Clinical TrialsSample Size for Survival Trials in CancerEdward Lakatos Non-Inferiority Trials Rajeshwari Sridhara and Thomas Gwise Quality of Life Diane Fairclough Personalized Medicine Biomarker-Based Clinical Trials Edward L. Korn and Boris Freidlin Adaptive Clinical Trial Designs in Oncology J. Jack Lee and Lorenzo Trippa Dynamic Treatment Regimes Marie Davidian, Anastasios (Butch) Tsiatis, and Eric Laber Index