Essentials of Domestic Animal Embryology (Paperback)

CONTENTS
INTRODUCTION & GENERAL PRINCIPLES

1 Cellular and Molecular Mechanisms of Morphogenesis
? Cell proliferation: Cell cycle, differentiation, regulation
? Cell demise: Apoptosis
? Cytoskeleton/Extracellular Matrix/Cell-Matrix interactions
? Morphogenesis & Patterning

2 Comparative Gestation
? Distinctions of the Early Embryo, Embryonic and Fetal Periods of Gestation
? Species Variations Effecting Gestation Length: Companion, Domestic, Wildlife and Laboratory Animals
? Reproductive Cycles: Hormones, Estrous, Organs, Seasonal
? Fecundity: Survival Strategies, Conception Rates

DIFFERENTIATION OF GERM LAYERS

3. Gametogenesis
? Mitosis/Meiosis
? Oogenesis
? Spermatogenesis
? Veterinary Clinical Applications/Cases

4. Fertilization
? Acrosome Reaction
? Sperm-Zona Pellucida Interactions
? Gamete Fusion
? Blocks to Polyspermy
? Syngamy and Embryo Activation
? Veterinary Clinical Applications/Cases

5. Embryo Cleavage and Blastulation
? Polarity, Compaction and Cavitation
? Embryonic Disc, Primitive Streak and Formation of the Bilaminar Embryo
? Veterinary Clinical Applications/Cases

6. Gastrulation, Body Folding and Coelom Formation
? Notocord, Neural Tube and Segmentation
? Differentiation of Ectoderm, Mesoderm and Endoderm
? Body Folding, Coelom Formation and Lung Development
? Veterinary Clinical Applications/Cases

7. Development of the Peripheral Nervous System
? Spinal Cord and Motor/Sensory Innervation
? Somite Development

8. Comparative Placentation
? Extraembryonic Membranes: Amnion, Yolk Sac, Allantois, Chorion
? Placental Strategies: Choriovitelline, Chorioallantoic
? Species Variations
? Veterinary Clinical Applications/Cases

SYSTEMS DEVELOPMENT

9. Development of the Limbs
? Limb Bud Formation
? Apical Ectodermal Ridge
? Development of the Appendicular Skeleton, Musculature, Vasculature and Innervation
? Differentiation of Distal Appendages: Digit Formation
? Veterinary Clinical Applications/Cases

10. Development of the Heart
? Primitive Heart Tube Formation
? Development of Heart Chambers and Valves
? Development of the Conduction System
? Veterinary Clinical Applications/Cases

11. Development of the Vascular System
? Formation of the Aortic Arches and the Arterial System
? Development of the Vitelline, Umbilical and Cardinal Venous System
? The Coronary Vasculature
? Circulatory changes at Parturition
? Veterinary Clinical Applications/Cases

12. Development of the Gastrointestinal System
? The Enteric Canal
? Stomach, Pancreas, Liver and Spleen
? Development of Peritoneum and Formation of Mesenteries
? Rotation and Fixation of the Midgut
? Differentiation of the Large Bowel
? Septation and Differentiation of the Cloaca
? Veterinary Clinical Applications/Cases

13. Development of the Urogenital System
? Pronephros Differentiation
? Development of the Mesonephric and Metanephric Kidneys
? Urogenital Ridge and Gonad Development
? Development of the Urogentital Duct Systems and External Genitalia
? Veterinary Clinical Applications/Cases

14. Development of the Head and Neck
? Development of the Skull and Vertebrae
? Differentiation of Pharyngeal Arch Structures and Pouch Derivatives
? Development of the Palate, Tongue and Pituitary
? Development of Facial Structures
? Veterinary Clinical Applications/Cases

15. Development of the Brain and Cranial Nerves
? Regional Differentiation and Functional Relationships
? Development of the Ventricular System
? Development and Function of the Cranial Nerves
? Veterinary Clinical Applications/Cases

16. Development of the Eyes and Ears
? Formation of the Ear
? Formation of the Eye
? Veterinary Clinical Applications/Cases

17. Development of the Integumentary System
? Differentiation of the Epidermis and Dermis
? Development of Epidermal Glands including Mammary Glands
? Formation of Hair and Teeth
? Veterinary Clinical Applications/Cases

CLINICAL AND APPLIED SYSTEMS

18. Teratology
? Genetic & Congenital
? Critical Periods & Teratogenic Agents
? Maternal/Fetal Interactions
? Specie-Specific Manifestations

19. Assisted Reproductive Technologies
? Artificial Insemination and Embryo/Gamete Transfer (ET,GIFT, ZIFT, etc)
? Cryopreservation of Germplasm
? In Vitro Maturation, Fertilization and Embryo Production
? Embryo Micromanipulation: Splitting, ICSI, Transgenics, Embryonic Stem Cells/ Chimeras, Cloning

20. Applied Embryology: Veterinary and Societal Issues
? The Role of the Veterinarian
? Contemporary Issues

Additional Reading - References
Glossary
Index