Advances in Statistical Methods for the Health Sciences: Applications to Cancer and AIDS Studies, Genome Sequence Analysis, and Survival Analysis (Hardcover)

Preface Contributors List of Tables List of Figures Part I: Prognostic Studies and General Epidemiology Systematic Review of Multiple Studies of Prognosis: The Feasibility of Obtaining Individual Patient Data \ D.G. Altman, M. Trivella, F. Pezzella, and A.L. Harris On Statistical Approaches for the Multivariate Analysis of Prognostic Marker Studies \ N. Hollander and W. Sauerbrei Where Next for Evidence Synthesis of Prognostic Marker Studies? Improving the Quality and Reporting of Primary Studies to Facilitate Clinically Relevant Evidence-Based Results \ R.D. Riley, K.R. Abrams, P.C. Lambert, A.J. Sutton, and D.G. Altman Part II: Pharmacovigilance Sentinel Event Methods for Monitoring Unanticipated Adverse Events \ P.A. Lachenbruch and J. Wittes Spontaneous Reporting System Modelling for the Evaluation of Automatic Signal Generation Methods in Pharmacovigilance \ E. Roux, F. Thiessard, A. Fourier, B. Begaud, and P. Tubert-Bitter Part III: Quality of Life Latent Covariates in Generalized Linear Models: A Rasch Model Approach \ K.B. Christensen Sequential Analysis of Quality of Life Measurements with the Mixed Partial Credit Model \ V. Sebille, T. Challa, and M. Mesbah A Parametric Degradation Model Used in Reliability, Survival Analysis, and Quality of Life \ M. Nikulin, L. Gerville-Reache, and S. Orazio Agreement Between Two Ratings with Different Ordinal Scales \ S. Natarajan, M.B. McHenry, S. Lipsitz, N. Klar, and S. Lipshultz Part IV: Survival Analysis The Role of Correlated Frailty Models in Studies of Human Health, Ageing, and Longevity \ A. Wienke, P. Lichtenstein, K. Czene, and A.I. Yashin Prognostic Factors and Prediction of Residual Survival for Hospitalized Elderly Patients \ M.L. Calle, P. Roura, A. Arnau, A. Yanez, and A.Leiva New Models and Methods for Survival Analysis of Experimental Data \ G.V. Semenchenko, A.I. Yashin, T.E. Johnson, and J.W. Cypser Uniform Consistency for Conditional Lifetime Distribution Estimators Under Random Right-Censorhip \ P. Deheuvels and G. Derzko Sequential Estimation for the Semiparametric Additive Hazard Model \ L. Bordes and C. Breuils Variance Estimation of a Survival Function with Doubly Censored Failure Time Data \ C. Zhu and J. Sun Part V: Clustering Statistical Models and Artificial Neural Networks: Supervised Classification and Prediction Via Soft Trees \ A. Ciampi and Y. Lechevallier Multilevel Clustering for Large Databases \ Y. Lechevallier and A. Ciampi Neural Networks: An Application for Predicting Smear Negative Pulmonary Tuberculosis \ A.M. Santos, B.B. Pereira, J.M. Seixas, F.C.Q. Mello, and A.L. Kritski Assessing Drug Resistance in HIV Infection Using Viral Load Using Segmented Regression \ H. Liang, W.-Y. Tan, and X. Xiong Assessment of Treatment Effects on HIV Pathogenesis Under Treatment by State Space Models \ W.-Y. Tan, P. Zhang, X. Xiong, and P. Flynn Part VI: Safety and Efficacy Assessment Safety Assessment Versus Efficacy Assessment \ M.A. Foulkes Cancer Clinical Trials with Efficacy and Toxicity Endpoints: A Simulation Study to Compare Two Nonparametric Methods \ A. Letierce and P. Tubert-Bitter Safety Assessment in Pilot Studies When Zero Events are Observed \ R.E. Carter and R.F. Woolson Part VII: Clinical Designs An Assessment of Up-and-Down Designs and Associated Estimators in Phase I Trials \ H.K.T. Ng, S.G. Mohanty, and N. Balakrishnan Design of Multicentre Clinical Trials with Random Enrolment \ V.V. Anisimov and V.V. Fedorov Statistical Methods for Combining Clinical Trial Phases II and III \ N. Stallard and S. Tod