The Blood-Brain Barrier and Drug Delivery to the Cns (Hardcover)

History and Physiology of the Blood-Brain Barrier in Relation to Delivery of Drugs to the BrainMichael W. BradburyPhysicochemical Factors that Influence Brain UptakeMichael H. Abraham and James A. PlattsThe Development of In Vitro Models for the Blood-Brain and Blood-CSF BarriersChristiane Engelbertz, Dorothea Korte, Thorsten Nitz, Helmut Franke, Matthias Haselbach, Joachim Wegener, and Hans-Joachim GallaIn Vitro Models of the Blood-Brain Barrier and Their Use in Drug DevelopmentR. Cecchelli, B. Dehouck, L. Descamps, L. Fenart, V. Buee-Scherrer, C. Duhem, G. Torpier, and M. P. DehouckThe Application of Microdialysis Techniques to the Study of Drug Transport Across the Blood-Brain BarrierA. G. de Boer, Elizabeth C. M. de Lange, Inez C. J. van der Sandt, and Douwe D. BreimerThe Role of Brain Extracellular Fluid Production and Efflux Mechanisms in Drug Transport to the BrainDavid J. Begley, Anthony Regina, Francoise Roux, Ehsan Ullah Khan, Christopher Rollinson, and Joan AbbottThe Relevance of P-Glycoprotein in Drug Transport to the Brain: The Use of Knockout Mice as a Model SystemUlrich MayerSpecific Mechanisms for Transporting Drugs Into BrainAkira TsujiDrug Metabolism in the Brain: Benefits and RisksAlain Minn, Ramon D. S. El-Bacha, Claire Bayol-Denizot, Philippe Lagrange, Funmilayo G. Suleman, and Daniela GradinaruTargeting Macromolecules to the Central Nervous SystemUlrich BickelUsing Nanoparticles to Target Drugs to the Central Nervous SystemJorg Kreuter and Renad N. AlyautdinBasic CNS Drug Transport and Binding Kinetics In VivoAlbert Gjedde, Antony D. Gee, and Donald Frederick Smith