Smith and Williams' Introduction to the Principles of Drug Design and Action (Paperback, 4 ed)

Processes of Drug Handling by the Body. The Design of Drug Delivery Systems. Fundamental Pharmacokinetics. Intermolecular Forces and Molecular Modeling. Drug Chirality and its Pharmacological Consequences. Quantitative Structure?Activity Relationships (QSAR) in Drug Design. Prodrugs. From Program Sanction to Clinical Trials: A Partial View of the Quest for Arimidex, A Potent, Selective Inhibitor of Aromatase. Design of Enzyme Inhibitors as Drugs. Peptide Drug Design. Combinatorial Chemistry: A Tool for Drug Discovery. Recombinant DNA Technology: Monoclonal Antibodies. The Human Genome and its Impact on Drug Discovery and Therapy. The Chemotherapy of Cancer. Neurotransmitters, Agonists, and Antagonists. Design of Antibacterial, Antifungal, and Antiviral Agents. Pharmaceutical Applications of Bioinorganic Chemistry. Index.