Applications of Genome Modulation and Editing (Hardcover)

· 제목 : Applications of Genome Modulation and Editing (Hardcover) 
· 분류 : 외국도서 > 과학/수학/생태 > 과학 > 생명과학 > 유전학/유전체학
· ISBN : 9781071623008
· 쪽수 : 369쪽
· 출판일 : 2022-06-14

Part I: Gene Editing Approaches

1.              Historical DNA manipulation Overview

LLuis Montoliu

 

2.              Tools for efficient genome editing; ZFN, TALEN, and CRISPR

Yasaman Shamshirgaran,^,Jun Liu, Huseyin Sumer, Paul J. Verma and Amir Taheri-Ghahfarokhi

 

Part II: Genetic Manipulation Methods

3.              Efficient generation of stable cell lines with inducible neuronal transgene expression using the piggyBac transposon system

Jinchao Gu, Huseyin Sumer and Brett Cromer

 

4.              Modifying Bacterial Artificial Chromosomes for Extended Genome Modification Hannah Auch, Nikolai Klymiuk and Petra Runa-Vochozkova 

 

5.              Site specific editing of the genome in Pluripotent cells Luis Ortega and Joseph Rosenbluh

 

6.              Targeting the AAVS1 site with transgene cassette by CRISPR/Cas9 with an inducible transgene cassette for the to neuronal differentiation of human pluripotent stem cells

Jinchao Gu, Ben Rollo, Huseyin Sumer and Brett Cromer

 

7.              Microinjection of zygotes for CRISPR/Cas9 mediated insertion of transgenes into the murine Rosa26 safe harbour

Fabien Delerue and Lars M. Ittner

 

8.              CRISPR-on for endogenous activation of SMARCA4 expression in bovine embryos

Virgilia Alberio, Virginia Savy and Daniel F. Salamone

 

Part III: Applications of Genome Manipulation

9.              CRISPR/Cas mutagenesis to generate novel traits in Bactrocera tryoni for Sterile Insect Technique

Amanda Choo, Elisabeth Fung, Thu N.M. Nguyen, Anzu Okada and Peter Crisp

 

10.           CRISPR/Cas9 Genome Editing in the New World Screwworm and Australian Sheep Blowfly

 Daniel F. Paulo, Megan E. Williamson and Maxwell J. Scott

 

11.           Generation of gene drive mice for invasive pest population suppression

Mark Bunting, Chandran Pfitzner, Luke Gierus, Melissa White, Sandra Piltz and Paul Thomas

 

Part IV: Large animal models of human disease

12.           Generation of a?human deafness sheep model using the CRISPR/Cas system

Martina Crispo, Vanessa Chenouard, Pedro dos Santos-Neto, Laurent Tesson, Marcela Souza, JeanMarie Heslan, Federico Cuadro, Ignacio Anegon and Alejo Menchaca

 

13.           Targeted Gene Editing in Porcine Germ Cells

Taylor Goldsmith, Alla Bondareva, Dennis Webster, Anna Laura Voigt, Lin Su, Daniel F. Carlson and Ina Dobrinski

 

14.           Generating a Heat Tolerance Mouse Model

Jun Liu and Paul J. Verma

 

Part V: Large Animal Welfare and Production Outcomes

15.           Generation of pigs that produce single sex progeny

 Bjorn Petersen and Stefanie Kurtz

 

16.           Generation of Double-muscled Sheep and Goats by CRISPR/Cas9-mediated Knockout of the Myostatin Gene

Peter Kalds, Martina Crispo, Chao Li, Laurent Tesson, Ignacio Anegon, Yulin Chen, Xiaolong Wang and Alejo Menchaca

 

Part VI: Concluding Remarks

17.           Regulatory and policy considerations around applications of genome editing in agriculture

 Steffi Friedrichs, Karinne Ludlowand Peter Kearns