[eBook Code] Clinical Pharmacology and Therapeutics (eBook Code, 9th)

Contributors, vi

Preface, vii

Foreword, ix

Part 1 Principles of clinical pharmacology

1 Pharmacodynamics and pharmacokinetics, 3

2 Clinical trials and drug development, 11

Part 2 Aspects of therapeutics

3 Drugs and gastrointestinal disease, 19

4 Management of coronary artery disease and its complications, 29

5 Primary and secondary prevention of cardiovascular disease, 52

6 Drugs used to treat respiratory disease, 71

7 Drugs used to treat neurological disease, 81

8 Treatment of psychiatric disorders, 97

9 Antimicrobial therapy, 111

10 HIV and antiretroviral treatment, 132

11 Travel medicine and tropical disease, 143

12 Drugs and endocrine disease, 153

13 Drugs and the reproductive system, 169

14 Drugs and the urological system, 178

15 Cancer therapeutics, 185

16 Drugs and infl ammatory joint disease, 197

17 Immunopharmacology, 204

18 Drugs and the blood including anticoagulants and thrombolytic drugs, 215

19 Drugs used for pain relief and anaesthesia, 228

Part 3 Practical aspects of prescribing

20 Clinical pharmacokinetics: dosage individualisation, 241

21 Influence of renal and hepatic disease on pharmacokinetics and pharmacodynamics, 247

22 Prescribing for the young and the elderly, 252

23 Drugs in pregnant and breastfeeding women, 255

24 Pharmacoeconomics: the economic evaluation of new drugs, 262

25 Poisoning and drug overdose, 269

26 Drugs you may need in a hurry, 283

27 Prescribing and its pitfalls, 287

Self assessment questions, 294

Self assessment answers, 299

Index, 302