[eBook Code] Plant Chemical Biology (eBook Code, 1st)

Preface vii

Contributors ix

part one Introduction 1

1.1 From Herbal Remedies to Cutting-Edge Science: A Historical Perspective of Plant Chemical Biology 3
Michelle Q. Brown, Abel Rosado, and Natasha V. Raikhel

part Two Sources of small molecules 19

2.1 Compound Collections 21
Reg Richardson

2.2 Combinatorial Chemistry Library Design 40
Robert Klein and Stephen D. Lindell

2.3 Natural Product-Based Libraries 64
Alan L. Harvey

part three Identification of new chemical tools by High-Throughput Screening 73

3.1 Assay Design for High-Throughput Screening 75
Frank W. An and Jose R. Perez

part four Use of chemical biology to study plant physiology 93

4.1 Use of Chemical Biology to Understand Auxin Metabolism, Signaling, and Polar Transport 95
Ken-ichiro Hayashi and Paul Overvoorde

4.2 Brassinosteroids Signaling and Biosynthesis 128
Takeshi Nakano and Tadao Asami

4.3 Chemical Genetic Approaches on ABA Signal Transduction 145
Eunjoo Park and Tae-Houn Kim

4.4 Jasmonic Acid 160
Christian Meesters and Erich Kombrink

4.5 Chemical Genetics as a Tool to Study Ethylene Biology in Plants 184
Yuming Hu, Filip Vandenbussche, and Dominique Van Der Straeten

part five Use of chemical biology to study plant cellular processes 203

5.1 The Use of Small Molecules to Dissect Cell Wall Biosynthesis and Manipulate the Cortical Cytoskeleton 205
Darby Harris and Seth DeBolt

5.2 The Use of Chemical Biology to Study Plant Cellular Processes: Subcellular Trafficking 218
Ash Haeger, Malgorzata £angowska, and Stéphanie Robert

part six Target identification 233

6.1 Target Identification of Biologically Active Small Molecules 235
Paul Overvoorde and Dominique Audenaert

part seven Translation of plant chemical biology from the lab to the field 247

7.1 Prospects and Challenges for Translating Emerging Insights in Plant Chemical Biology into New Agrochemicals 249
Terence A. Walsh

7.2 In Vitro Propagation 263
Hans Motte, Stefaan Werbrouck, and Danny Geelen

Index 289