Alcohol Abuse and Liver Disease (Hardcover)

List of Contributors vii

Preface xi

1 Epidemiology of alcohol use 1
Ian Gilmore and William Gilmore

2 Epidemiology of alcoholi¿½]related liver disease 11
Ed Britton and Martin Lombard

3 Alcoholism: diagnosis and natural history in the context of medical disease 23
Thomas P. Beresford Narin Wongngamnit and Benjamin A. Temple

4 Alcohol and other substance misuse 35
John B. Saunders

5 Risk factors for alcoholi¿½]related liver disease 47
Stuart Kendrick and Chris Day

6 Mechanisms of alcohol toxicity 55
Guruprasad P. Aithal and Jane I. Grove

7 Extrahepatic manifestations of alcohol excess 65
Karli¿½]Heinz Schulz Sandra van Eckert and Jens Reimer

8 Patterns of alcoholi¿½]associated liver damage 79
Peter Hayes and Michael Williams

9 Cofactors and alcoholi¿½]related liver disease 87
John G. O’Grady

10 Impact of alcohol and liver disease on prescribing 91
Richard Parker and Amanda Smith

11 Psychiatric examination of liver transplant patients with alcohol use disorders 99
Robert M. Weinrieb and Omair Abbasi

12 Abnormal liver tests in the context of alcohol excess 109
James Ferguson

13 Biochemical determination of alcohol consumption 113
Friedrich Martin Wurst Natasha Thon Wolfgang Weinmann Michel Yegles Jessica Wong and Ulrich W. Preuss

14 The role of histology 123
Desley A.H. Neil

15 General assessment and management 135
Patrizia Burra and Giacomo Germani

16 Brief alcohol interventions 147
Stephanie Scott and Eileen Kaner

17 Alcohol withdrawal syndrome: diagnosis and treatment 155
Julie Taub and Thomas P. Beresford

18 Psychosocial treatments of alcohol use disorders 165
Terry D. Schneekloth

19 Pharmacologic interventions 175
Renata Yang and Marian Fireman

20 Treatment of extrahepatic manifestations of alcohol abuse 187
Joaquim Fernandezi¿½]Sola

21 Treatment of liver disease 197
James Neuberger

22 Treatment of alcoholic hepatitis 203
Mark Thursz and Stephen Atkinson

23 Liver transplantation in people with alcoholi¿½]related liver disease 215
Santiago Tome and Michael R. Lucey

24 Future directions: the need for early identification and intervention for patients with excessive alcohol use 223
Andrea DiMartini Shari Rogal and Stephen Potts

Index 235