Chemical Engineering in the Pharmaceutical Industry: Drug Product Design, Development, and Modeling (Hardcover, 2)

Preface

Contributors

Unit Conversions and Commonly used Formulas

Part I Introduction

Chapter 1 Chemical Engineering in the Pharmaceutical Industry: An Introduction

Part II Drug Product Design, Development & Modeling

Chapter 2 Design of Solid Dosage Formulations

Chapter 3 Powder Process Challenges and Solutions

Chapter 4 Design and Scale-up of Dry Granulation Processes

Chapter 5 Model based development of roller compaction processes

Chapter 6 Wet Granulation Processes

Chapter 7 Towards a generic model for twin-screw wet granulation

Chapter 8 Modeling a dosator capsule filling process for hard-shell capsules

Chapter 9 Powder Compaction – Process Design and Understanding

Chapter 10 Punch Sticking: Factors and Solutions

Chapter 11 Spray Atomization Modeling for Tablet Film Coating Processes

Chapter 12 Spray Drying and Amorphous Dispersions

Chapter 13 The Freeze Drying Process: The Use of Mathematical Modeling in Process Design, Understanding and Scale-up

Chapter 14 Sterilization Processes in the Pharmaceutical Industry

Chapter 15 Controlled Release Technology and Design of Oral Controlled Release Dosage Forms

Chapter 16 Process Design and Development for Novel Pharmaceutical Dosage Forms

Chapter 17 Multiscale Modeling of a Pharmaceutical Fluid-bed Coating Process: Using CFD/DEM and Population-balance Models to Predict Coating Uniformity

Chapter 18 Process Design of Topical Semi-solids: Application of Fundamental Concepts in Pharmaceutical Engineering to PEG Ointment Development

Chapter 19 Achieving a Hot Melt Extrusion Design Space for the Production of Solid Solutions

Chapter 20 Drug Product Process Modeling

Part III Continuous Manufacturing

Chapter 21 Continuous Manufacturing in Secondary Production

Chapter 22 Continuous Direct Compression Using Portable Continuous Miniature Modular & Manufacturing (PCM&M)

Chapter 23 Process control levels for continuous pharmaceutical tablet manufacturing

Part IV Applied Statistics / Regulatory Environment

Chapter 24 Multivariate Analysis for Pharmaceutical and Medical Device Development

Chapter 25 Pharmaceutical Manufacturing: The Role of Multivariate Analysis in Design Space, Control Strategy, Process Understanding, Troubleshooting, and Optimization

Chapter 26 Quality by Design:  Pilot to Reality - The Honeymoon Phase to the Stormy Years