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· 분류 : 외국도서 > 의학 > 정신의학 > 일반
· ISBN : 9781119442608
· 쪽수 : 872쪽
· 출판일 : 2018-07-16
목차
Part 1: Drug treatment of major psychiatric conditions
Chapter 1: Schizophrenia and related psychoses
ANTIPSYCHOTIC DRUGS
General introduction
General principles of prescribing
Minimum effective doses
Licensed maximum doses
Equivalent doses
High-dose antipsychotics: prescribing and monitoring
Combined antipsychotics
Antipsychotic prophylaxis
Negative symptoms
Monitoring
Relative adverse effects – a rough guide
Treatment algorithms for schizophrenia
First-generation antipsychotics – place in therapy
NICE guidelines for the treatment of schizophrenia
Antipsychotic response – to increase the dose, to switch, to add or just wait – what is the right move?
Acutely disturbed or violent behaviour
Antipsychotic long-acting injections
Depot antipsychotics – pharmacokinetics
Management of patients on long-term depots
Aripiprazole long-acting injection
Olanzapine long-acting injection
Paliperidone palmitate long-acting injection
Risperidone long-acting injection
Omega-3 fatty acid (fish oils) in schizophrenia
ANTIPSYCHOTIC ADVERSE EFFECTS
Extrapyramidal symptoms
Akathisia
Weight gain
Treatment of antipsychotic-induced weight gain
Electroconvulsive therapy and psychosis
Neuroleptic malignant syndrome
Catatonia
QT prolongation
Dyslipidaemia
Diabetes and impaired glucose tolerance
Blood pressure changes
Hyponatraemia
Hyperprolactinaemia
Sexual dysfunction
Pneumonia
Switching antipsychotics
Venous thromboembolism
REFRACTORY SCHIZOPHRENIA AND CLOZAPINE
Clozapine initiation schedule
Optimising clozapine treatment
Alternatives to clozapine
Re-starting clozapine after a break in treatment
Initiation of clozapine for community-based patients
CLOZAPINE ADVERSE EFFECTS
Clozapine: common adverse effects
Clozapine: uncommon or unusual adverse effects
Clozapine: serious haematological and cardiovascular adverse effects
Clozapine-induced hypersalivation
Clozapine-induced gastrointestinal hypomotility (CIGH)
Clozapine, neutropenia and lithium
Clozapine and chemotherapy
Chapter 2: Bipolar disorder
Lithium
Valproate
Carbamazepine
Antipsychotic drugs in bipolar disorder
Antipsychotic long-acting injections in bipolar disorder
Physical monitoring for people with bipolar disorder
Treatment of acute mania or hypomania
Rapid-cycling bipolar disorder
Bipolar depression
Prophylaxis in bipolar disorder
Chapter 3: Depression and anxiety disorders
Chapter 4 Addictions and substance misuse
Introduction
Alcohol dependence
Opioid dependence
Nicotine and smoking cessation
Pharmacological treatment of dependence on stimulants
GHB and GBL dependence
Benzodiazepine misuse
Synthetic cannabinoid receptor agonists (SCRAs)
Interactions between ‘street drugs’ and prescribed psychotropic drugs
Drugs of misuse – a summary
Part 2: Drug treatment of special patient groups
Chapter 5 Children and adolescents
Principles of prescribing practice in childhood and adolescence
Depression in children and adolescents
Bipolar illness in children and adolescents
Psychosis in children and adolescents
Anxiety disorders in children and adolescents
Obsessive compulsive disorder (OCD) in children and adolescents
Post-traumatic stress disorder in children and adolescents
Attention deficit hyperactivity disorder
Autism spectrum disorders
Tics and Tourette’s syndrome
Melatonin in the treatment of insomnia in children and adolescents
Rapid tranquillisation (RT) in children and adolescents
Doses of commonly used psychotropic drugs in children and adolescents
Chapter 6 Prescribing in older people
General principles
Dementia
Safer prescribing for physical conditions in dementia
Management of behavioural and psychological symptoms of dementia
A guide to medication doses of commonly used psychotropic drugs in older adults
Covert administration of medicines within food and drink
Chapter 7: Pregnancy and breastfeeding
Drug choice in pregnancy
Breastfeeding
Chapter 8: Hepatic and renal impairment
Hepatic impairment
Renal impairment
Part 3: Prescribing in specialist conditions
Chapter 9: Drug treatment of other psychiatric conditions
Borderline personality disorder
Eating disorders
Delirium
Chapter 10: Drug treatment of psychiatric symptoms occurring in the context of other disorders
General principles of prescribing in human immunodeficiency virus (HIV)
Prescribing psychotropics in HIV
Epilepsy
22q11.2 Deletion syndrome
Learning disabilities
Huntington’s disease
Multiple sclerosis
Parkinson’s disease
Atrial fibrillation
Bariatric surgery
Part 4: Other aspects of psychotropic drug use
Chapter 11 Pharmacokinetics
Plasma level monitoring of psychotropic drugs
Interpreting post-mortem blood concentrations
Acting on clozapine plasma concentration results
Psychotropic drugs and cytochrome (CYP) function
Smoking and psychotropic drugs
Drug interactions with alcohol
Chapter 12 Other substances
Caffeine
Nicotine
Chapter 13: Psychotropic drugs in special conditions
Psychotropic drugs in overdose
Driving and psychotropic drugs
Psychotropic drugs and surgery
Chapter 14: Miscellany
Enhancing medication adherence
Re-starting psychotropic medications after a period of non-compliance
Biochemical and haematological effects of psychotropic medications
Summary of psychiatric adverse effects of non-psychotropic medications
Prescribing drugs outside their licensed indications (‘off-label’ prescribing)
The Mental Health Act in England and Wales
Site of administration of intramuscular injections
