Developmental Toxicology (Paperback, 3 ed)

1. Role of Apoptosis in Normal and Abnormal Development. 2. Signal transduction pathways as targets for teratogens. 3. Nutrition in Developmental Toxicology. 4. Epigenetic Mechanisms-Role of DNA Methylation, Histone Modifications and Imprinting. 5. Personalized Nutrition and Medicine in Perinatal Development. 6. Targeted Gene changes affecting Developmental Toxicity. 7. Use of mammalian in vitro systems, including embryonic stem cells, in developmental toxicity testing. 8. Zebrafish: a Non-Mammalian Model of Developmental Toxicology. 9. Physiologically-Based Pharmacokinetic Modeling in the risk assessment of developmental toxicants. 10. Integration of whole animal developmental toxicity data into risk assessment. 11. Genomic Approaches in Developmental Toxicology. 12. Comparative Bioinformatics and Computational Toxicology. 13. Investigating Drug Effects in Human Pregnancy.