Reversibility of Chronic Degenerative Disease and Hypersensitivity, Volume 1: Regulating Mechanisms of Chemical Sensitivity (Hardcover)

Chapter 1 The Physiologic Basis of HomeostasisIntroductionOverview of the Dynamics of Noxious Incitant Entry and Fate The Nature of the Incitant Stimulus The Nature of the Body’s Homeostatic ResponseThe Nature of Information Intake and DistributionAutomating the Body?EnergyThe Clinical Signs and Symptoms after Chronic Noxious Incitant EntryThe Body’s Communication System?The Ground Regulation SystemAnatomical Categories Used in Communication for Regulating Homeostatic MechanismSkin and Mucous MembranesConnective Tissue MatrixMechanical Support System (Support Structure) Communication System Properties Connective Tissue and Electromagnetic Energy Molecular Sieve Latent Free Radical Response Vascular Function?Homeostasis Diffusion Vascular Sieve Microcirculation Vascular Tone Lymphatics Intravascular Content Cells Plasma Proteins Plasma Lipids Neurological Aspects of HomeostasisPollutant Entry and the Body’s Homeostatic Response to and Fate of the Noxious Stimuli Total Environmental Load Total Body Load The Local Receptors Local Homeostatic Responses and Information Reception Matrix Receptor Adjustment Responses Local Cell and Matrix Reactions for the Adjustment Response Regional Homeostatic Adjustment Central Homeostasic Adjustment Principles and Facts about Adjustment Responses Defense System Redox System LatencyThe Early Defense Mechanism Tissue Response to Local Entry (Initially Sub Inflammatory) Immune Response Nonimmune Detoxification in Relation to Homeostasis and the Defense Mechanism Repair Mechanism?Healing The Nonspecific Mesenchyme Reaction Rate of Enzyme and Nutrient Deficiency Homeostatic Dysfunction Leading to a Disordered Homeostatic Response Periodic Response Aperiodic ResponseThe Specific Mechanisms of Inflammation and Function of Neutrophils and Macrophages Proinflammatory Cytokines Interleukin-6Neurological System Connection with the Connective Tissue Matrix and InflammationSummaryReferences AMPLIFICATION SYSTEMS: NEUROLOGICAL, IMMUNE, AND ENDOCRINE Chapter 2 Nervous SystemIntroduction Linear and Biphasic Effects of Noxious Stimuli EntryReceptorsAutonomic Nervous System Anatomy and Physiology of the Peripheral Autonomic Nervous System Central Connection of the Autonomic Nervous System with the Hypothalamus Reflex Pathways Dysfunction of the Autonomic Nervous SystemDenervation Supersensitivity Law of Denervation Denervation and Spondylosis: Neuropathic Pain Neurally Mediated Hypotension and Tachycardia Neuromuscular Hypotension and Chronic Fatigue Reflex Sympathetic Dystrophy (Causalgia)Pollutant Injury to the EyePollutant Injury to the Nervous System of the EyeCranial NervesAutonomic NervesNeurogenic Vascular Responses to Pollutant StimuliPathogenesis of Neuroimmunological Mediators (Neuropeptide Triggering by Noxious Stimuli)The Acupuncture Energy Flow System (AES)NAETVoluntary Central Nervous SystemNoxious Injury to the Blood-Brain BarrierNoxious Injury after Penetration of the Blood-Brain BarrierGeneral Principles of Neuronal PhysiologyPrinciples of Response after Toxic ExposureReversibility vs. Irreversibility of Cell Damage after Pollutant Exposure Mechanism of Acute Central Nervous System InjuryNeurological Effects of Toxic ChemicalsFixed-Named DiseaseToxic NeuropathySummaryReferences Chapter 3 Immune SystemIntroductionProperties of Entering Noxious Excitants Stem CellsLymph Nodes, Lymphatic Organs, and the Lymphatic System Development of Lymphatic Channels and LymphocytesRegionalization of the Immune Response by Lymphatic Tissue Nodes and Channels after Mucosal Entry Mucosa Associated Lymphoid Tissue (MALT); Nasal Associated Lymphoid Tissue (NALT); Bronchial Associated Lymphoid Tissue (BALT); Gut Associated Lymphoid Tissue (GALT)Neuroimmune RegulationThe Clinical Implications of Food and Chemical Sensitivity in Relation to the Autonomic Nervous System and Immune SystemImmunity Innate Immunity Transition to Innate and Humoral Immunity in the Newborn and Infant Acquired ImmunityLymphocytes The T-lymphocytes General Intrinsic MechanismsB-LymphocytesOnset of Antibodies Classes of Antibodies Inflammatory Effects Clinical Regulation of the Immune System The Cell Cycle Abnormal Cell Cycle Progression in Patients with Chronic Fatigue Syndrome (CFS) Cell Cycle and Cancer AutoimmunityFailure of the Tolerance Mechanism Causes Autoimmune DiseasesAutogenous Lymphocytic Factor (ALF)Cell DeathAllergy and HypersensitivityAging and the Immune SystemSummaryReferences Chapter 4 Endocrine SystemIntroductionIntegrated PhysiologyPituitary Gland Pollutant Effects on the Nervous System of the Pituitary GlandPollutant Effects on the Physiology of the Pituitary Growth HormonePineal GlandNeuroendocrine System (Paraganglia, Paraneuron) Neuroendocrine Phenotype Biosynthetic Profile Secretory Granules Specialization of Neuroendocrine Cells Topography of Neuroendocrine Cell Subsets Branchiomeric Group Intravagal Neuroendocrine Cells Visceral-Autonomic Paraganglion Cells Genitourinary Paraganglion Cells Paragangliomas Clinical Manifestations of Neuroendocrine StimulationAdrenal Glands Physiology of the Dynamics of Homeostasis and Dyshomeostasis in the Adrenal Glands Clinical Picture of Pollutant Injury and Adrenal Dysfunction Hyperadrenalism Adrenal Insufficiency/HypoadrenalismParathyroid GlandOvary Organization/Activation Hypothesis Male Homosexuality Sexual DysfunctionUterus and Tubes Premenstrual Syndrome Vasculitis of the Reproductive System Endometriosis Spontaneous Abortion Hormones The Influence of Toxics on Hormonal Homeostasis PCBs Pesticides/Herbicides Menopause DysfunctionVagina and VulvaTestes and Seminal Vesicles Mechanisms of Action and Fetal Vulnerability Hormones and Neurobehavioral Effect Beyond Endocrine Disruption Implications and Ongoing ActivitiesExogenous Estrogens Phytoestrogens Estrogens in Milk Estrogenic Chemicals Sertoli Cell Number and Sperm OutputThyroid Physiology and Pathophysiology Agents Acting Directly on the Thyroid Class I Class II Class III Class IV Class V Agents Acting Indirectly on the Thyroid General Properties, Distribution, and Epidemiology Sulfurated Organics Thiocyanate (SCN), Isothiocyanates, and Thioglycosides (Goitrin) Aliphatic Disulfides Polyphenols Phenolic and Phenolic-Carboxylic Derivatives 2,4-DNP Phthalate Esters and Phthalic Acid Derivatives: DHBAs PCBs and PBBs PAH, 3,4,-BaP, MCA, and 7,12-DMBASummaryReferences