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· 분류 : 외국도서 > 의학 > 약학
· ISBN : 9781493995035
· 쪽수 : 332쪽
· 출판일 : 2019-05-28
목차
1. Design Principles for Intestinal Permeability of Cyclic Peptides
Alan M. Mathiowetz
2. Strategies to Enhance Metabolic Stabilities
Bhavesh Khatri, Venkateswara Rao Nuthakki, and Jayanta Chatterjee
3. Designing Cell-Permeable Macrocyclic Peptides
George Appiah Kubi, Patrick G. Dougherty, and Dehua Pei
4. Computational Methods for Studying Conformational Behaviors of Cyclic Peptides
Fan Jiang and Hao Geng
5. Computational Opportunities and Challenges in Finding Cyclic Peptide Modulators of Protein-Protein Interactions
Fergal Duffy, Nikunj Maheshwari, Nicolae-Viorel Buchete, and Denis Shields
6. Design of Cyclic Peptides as Protein Recognition Motifs
Ye Che
7. Design and Synthetic Strategies for Helical Peptides
Licheng Tu, Dongyuan Wang, and Zigang Li
8. Click Chemistry for Cyclic Peptides Drug Design
Adel Ahmed Rashad
9. Frontier between Cyclic Peptides and Macrocycles
Philipp Ermert, Anatol Luther, Peter Zbinden, and Daniel Obrecht
10. Building upon Nature’s Framework: Overview of Key Strategies towards Increasing Drug-Like Properties of Natural Product Cyclopeptides and Macrocycles
Maria-Jesus Blanco
11. Design of Oxytocin Analogs
Kazimierz Wi?niewski
12. DNA-Encoded Macrocyclic Peptide Library
Zhengrong Zhu, Alex Shaginian, LaShadric C. Grady, Christopher P. Davie, Kenneth Lind, Sandeep Pal, Praew Thansandote, and Graham L. Simpson
13. Peptide Display Technologies
Anthony Pitt and Zeke Nims
14. Discovery of Functional Macrocyclic Peptides by Means of the RaPID System
Christos Tsiamantas, Manuel E. Otero-Ramirez, and Hiroaki Suga
15. Genetic Selections with SICLOPPS Libraries: Towards the Identification of Novel Protein-Protein Interaction Inhibitors and Chemical Tools
Francisco Castillo and Ali Tavassoli
