Drug-Device Combination Products : Delivery Technologies and Applications (Hardcover)

Part 1 Overview: Drug-device combination products; Enabling drug delivery from combination products; Nanomedical drug-device combination products. Part 2 Areas of application: Catheter-based drug-device combination products: An overview; Catheter-based drug-device combination products: The anti-infective 5-fluorouracil-coated central venous catheter; Future outlook for drug eluting stents (DES); Drug eluting beads (DEB) in the treatment of liver cancer; Antibiotic-loaded bone cements; Glass-ionomer cements as drug-device combination products; Bone graft substitutes as drug-device combination products; Antibacterial releasing dental restorative materials; Collagen-based dressings as therapeutic agents for wound healing; Drug-device combination products for occular applications. Part 3 Development of drug-device combination products: Safety and efficacy issues in designing drug-device combination products: The case of drug eluting stents (DES); Preclinical testing of drug-device combination products; Sterilisation of drug-device combination products; Innovation and patent issues in the development of drug-device combination products: The case of drug eluting stents (DES); Regulation of drug-device combination products in Europe; (28a) Regulation of drug-device combination products in the USA.