Biomaterials for Spinal Surgery (Hardcover)

Introduction to biomaterials for spinal surgery. Part 1 Fundamentals of biomaterials for spinal surgery: An overview of the challenges of bringing a medical device for the spine to the market; Introduction to spinal pathologies and clinical problems of the spine; Forces on the spine; Finite element modelling of the spine; Osteobiologic agents in spine surgery. Part 2 Spinal fusion and intervertebral discs: Spine fusion: cages, plates and bone substitutes; Artificial intervertebral discs; Biological response to artificial discs. Part 3 Vertobroplasty and scoliosis surgery: The use of polymethyl methacrylate (PMMA) in neurosurgery; Optimising the properties of injectable materials for vertebraplasty and kyphoplasty; Injectable calcium phosphates for vertebral augmentation; Composite injectable materials for vertebroplasty; Scoliosis implants: surgical requirements; Shape memory, superelastic and low Young’s modulus alloys. Part 4 Regenerative medicine in the spine: Cell-based tissue engineering approaches for disc regeneration; Angiogenesis control in spine regeneration; Stem cells for disc regeneration; Nucleus regeneration; In vivo models of regenerative medicine in the spine.