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· 분류 : 외국도서 > 의학 > 유전학
· ISBN : 9783030147945
· 쪽수 : 624쪽
· 출판일 : 2020-09-11
목차
Chapter 1. Establishment, Erasure and Synthetic Reprogramming of DNA Methylation in Mammalian Cells.- Chapter 2. Origin and Mechanisms of DNA Methylation Dynamics in Cancers.- Chapter 3. CpG Islands Methylation Alterations in Cancer: Functionally Intriguing Security Locks, Useful Early Tumor Biomarkers.- Chapter 4. Histone and DNA Methylome in Neurodegenerative, Neuropsychiatric and Neurodevelopmental Disorders.- Chapter 5. DNA Methylation in Neuronal Development and Disease.- Chapter 6. Functional Implications of Dynamic DNA Methylation for the Developing, Aging and Diseased Brain.- Chapter 7. The Methylome of Bipolar Disorder: Evidence from Human and Animal Studies.- Chapter 8. DNA Methylation in Multiple Sclerosis.- Chapter 9. Early Life Stress and DNA Methylation.- Chapter 10. Regulation of 5-hydroxymethylcytosine Distribution by the TET Enzymes.- Chapter 11. Epigenetic Alterations: The Relation Between Occupational Exposure and Biological Effects in Humans.- Chapter 12. DNA Methylation: Biological Implications and Modulation of its Aberrant Dysregulation.- Chapter 13. Functions and Dynamics of Methylation in Eukaryotic mRNA.- Chapter 14. The Role of mRNA m6A in Regulation of Gene Expression.- Chapter 15. G9a and G9a-like Histone Methyltransferases and Their Effect on Cell Phenotype, Embryonic Development, and Human Disease.- Chapter 16. Biomolecular Recognition of Methylated Histones.- Chapter 17. The Role of Protein Lysine Methylation in the Regulation of Protein Function - Looking Beyond the Histone Code.- Chapter 18. Secondary Structures of Histone H3 Proteins with Unmethylated and Methylated Lysine-4 and -9 Resiudes; Characterization Using Circular Dichroism Spectroscopy.- Chapter 19. Asymmetric Dimethylation on Arginine (ADMA) of Histones in Development, Differentiation and Disease.- Chapter 20. A Switch for Transcriptional Activation and Repression: Histone Arginine Methylation.- Chapter 21. Aberrant Epigenomic Regulatory Networks in Multiple Myeloma and Strategies for their Targeted Reversal.- Chapter 22. Metabolic Deregulations Affecting Chromatin Architecture: One-carbon Metabolism and Krebs Cycle Impact Histone Methylation.- Chapter 23. Histone Methylome of the Human Parasite Schistosoma Mansoni.