The M2 Macrophage (Hardcover)

Chapter 1. Introduction. What is an M2 macrophage? Historical overview of the macrophage polarization model. The Th1/Th2 and M1/M2 paradigms, the arginine fork.- Chapter 2. Evolutionary origin of the M2 macrophage activation: invertebrates.- Chapter 3. Evolution of M2 macrophage functions in chordates.- Chapter 4. Signal mechanisms of M2 macrophage activation.- Chapter 5. Mechanisms which control the size of M2 macrophage-dominated tissue macrophage niches.- Chapter 6.Immune functions of the M2 macrophages: host defense, self-tolerance and autoimmunity.- Chapter 7. M2 macrophages in the integument and in the musculoskeletal system.- Chapter 8. M2 macrophages in the circulatory-, respiratory and excretory organs.- Chapter 9. M2 macrophages in the metabolic organs and in the neuroendocrine system.- Chapter 10. Practical approaches in M2 macrophage biology: analysis, pharmacology and didactical interpretation of M2 macrophage functions.