Pharmacokinetics in Drug Development: Problems and Challenges in Oncology, Volume 4 (Paperback)

Overview of Oncology Drug Development.- A Global Perspective on First-In-Man Dose Selection: Oncology and Beyond.- Controversies in Oncology: Size-Based vs. Fixed Dosing.- Clinical QTc Assessment in Oncology.- Expediting Drug Development: Breakthrough Therapy Designation.- Pharmacokinetics and Pharmacodynamics of Tyrosine Kinase Inhibitors.- Combination Development.- Role of Pharmacokinetics-Pharmacodynamics in Biosimilar Assessments.- Pharmacokinetics and Pharmacogenetics of Metronomics.- Modeling Tumor Growth in Animals and Humans: an Evolutionary Approach.- Practical Considerations for Clinical Pharmacology in Oncology Drug Development: A Survey of Approvals from 2009-2015.- New Advancements in Exposure-Response Analysis to Inform Regulatory Decision-Making