Modular Protein Domains (Hardcover)

INTRODUCTION
An overview of protein to protein interactions and protein modules
SH2 domain as a paradigm of protein modules
PROTEIN BINDING DOMAINS THAT INTERACT WITH PROLINE LIGANDS
SH3 domain
WW domain
EVH1 domain
GYF domain
PROTEIN BINDING DOMAINS AND THEIR REGULATION BY PHOSPHORYLATION
PTB domain
FHA domains
14-3-3 proteins and phospho-serine/theronine binding modules
Protein kinase domains as important catalytic domains functionally linked to protein binding domains
PROTEIN DOMAINS REGULATING CHROMATIN FUNCTION
SET domains
Bromo domain
Chromo & Shadow-Chromo domains
PROTEIN DOMAINS RECOGNIZING SHORT PEPTIDE CORES IN THEIR LIGANDS
PDZ domain
EH domain
EXAMPLES OF FUNCTIONAL DIVERSITY AMONG PROTEIN DOMAINS: UBIQUITIN AND ACTIN BINDING DOMAINS
Ubiquitin-Binding Domains
CH domain
PHOSPHO-INOSITIDE BINDING PROTEIN DOMAINS
PH domain
VHS and ENTH domains
PX domain
DISSECTING DOMAINS AND LIGANDS WITH PEPTIDE CHEMISTRY AND COMPUTERS
Peptide and protein repertoires for global analysis of modules
Computational analysis of modular protein domains
Nomenclatures for protein modules and their cognate motifs
EPILOGUE: Future perspectives