Preparative Chromatography (Hardcover, 2, Completely Revi)

Preface

INTRODUCTION
On the Development of Chromatography
Focus of the Book
Recommendation to read this Book

FUNDAMENTALS AND GENERAL TERMINOLOGY
Principles of Adsorption Chromatography
Basic Effects and Chromatographic Definitions
Fluid Dynamics
Mass Transfer Phenomena
Equilibrium Thermodynamics
Thermodynamic Effects on Mass Separation

STATIONARY PHASES AND CHROMATOGRAPHIC SYSTEMS
Column Packings
Selection of Chromatographic Systems

CHROMATOGRAPHY EQUIPMENT: ENGINEERING AND OPERATION
Introduction
Engineering and Operational Challenges
Chromatography Columns Market
Chromatography Systems Market
Process Control
Packing Methods
Process Troubleshooting
Disposable Technology for Bio-Separations

PROCESS CONCEPTS
Discontinuous Processes
Continuous Processes
Choice of Process Concepts

MODELING AND MODEL PARAMETERS
Introduction
Models for Single Chromatographic Columns
Modeling HPLC plants
Calculations Methods
Parameter Determination
Experimental Validation of Column Models

MODEL BASED DESIGN, OPTIMIZATION AND CONTROL
Basic Principles and Definitions
Batch Chromatography
Recycling Chromatography
Conventional Isocratic SMB Chromatography
Isocratic SMB Chromatography under Variable Operating Parameters
Gradient SMB Chromatography
Multicolumn Systems for Bioseparations
Chromatographic SMB Reactors
Advanced Process Control

APPENDIX B
Data of Test Systems