Regulatory T Cells In Inflammation (Hardcover)

Origin, function and distribution of regulatory T cells.- History of CD25+CD4+ regulatory T cells.- “Natural” and “induced” regulatory T cells ? purpose and problems associated with an emerging distinction.- The role of interleukin-10 in regulatory-T-cell suppression: reconciling the discrepancies.- Activation and distribution of regulatory T cells in naive and antigen-stimulated immune systems.- Regulatory T cells and the innate immune system.- The potential use of regulatory T cells in immunotherapy.- Exploiting the potential of regulatory T cells in the control of type 1 diabetes.- Regulatory T cells in type 1 autoimmune diabetes.- The potential for targeting CD4+CD25+ regulatory T cells in the treatment of multiple sclerosis in humans.- Immunotherapy of rheumatoid arthritis using CD4+CD25+ regulatory T cells.- Potential for manipulation of regulatory T cells in treatment or prevention of allergic disease.- The role of regulatory T cells in cutaneous disorders.- The potential role of CD25+CD4+ regulatory T cells in the induction and maintenance of transplantation tolerance in humans.