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· 분류 : 외국도서 > 의학 > 내과학
· ISBN : 9784431682578
· 쪽수 : 802쪽
· 출판일 : 2012-01-11
목차
Prologue: how far have we come?.- What a dumb way to designate germs.- Recollections of a hepatitis investigator: 1940-1993.- The hepatitis viruses: accomplishments and problems.- How far have we come, and where are we going? 3 years after 1990.- How far have we come and where are we going?: pathogen-oriented prevention of hepatocellular carcinoma in Japan in 1993.- Hepatitis viruses A, B, C, D, & E.- 1. Perspectives.- The hepatitis viruses: an overview.- Recent advances in understanding the molecular virology of hepatoviruses: contrasts and comparisons with hepatitis C virus.- Hepatocarcinogenic mechanisms in hepadnavirus-infected hosts.- The hepatitis C virus: genetic organization, persistence, and vaccine strategies.- The molecular biology of hepatitis delta virus: recent advances.- Molecular and serological characteristics of hepatitis E virus.- 2. Taxonomy.- Classification and taxonomy of hepatitis viruses: summary of a Workshop.- Taxonomic classification of hepatitis A virus.- Classification and taxonomy of the hepadnaviruses: current status.- Derivation of a rational nomenclature for hepatitis C virus by phylogenetic analysis of the NS-5 region.- The taxonomy of hepatitis delta virus.- Hepatitis E virus: some characteristics relevant to virus classification.- New hepatitis virus(es)?.- New agent(s) to cause hepatitis?: summary of a Specialty Session.- Candidate hepatitis F virus in sporadic non-A, non-B acute liver failure: exclusion in liver of hepatitis viruses A, E, C and B by polymerase chain reaction.- Non-A, non-B, non-C, non-E acute hepatitis: does it really exist?.- Clinical and laboratory features of acute community-acquired non-A, non-B, non-C hepatitis.- Chronic non-A, non-B, non-C hepatitis in French blood donors assessed with HCV third-generation tests and polymerase chain reaction.- Evidence for parenterally transmitted non-A, non-B, non-C, non-D, non-E hepatitis in Russia.- Biology.- Molecular biology of hepatitis B virus.- Expression of defective hepatitis B (HBV)-DNA, synthesized from a singly spliced HBV-RNA, leads to cytoplasmic accumulation of capsid and X proteins.- Methods for the purification of enzymatically active reverse transcriptase of duck hepatitis B virus.- Some aspects of hepatitis C virus: a review and a hypothesis.- In vivo and in vitro replication, expression, processing, and assembly of hepatitis C virus: summary of a Speciality Session.- Molecular biology of pestiviruses and comparison with HCV.- Virus-like particles in the liver of an owl monkey inoculated with hepatitis C virus.- Useful markers for predicting in vivo infectivity of hepatitis C virus.- HCV-specific translation initiation.- Translation initiation mechanism on hepatitis C virus RNA.- Mapping of the internal ribosome entry site at the 5? end of the hepatitis C virus genome.- Secondary structure and protein-binding activities of the 5? nontranslated region of the hepatitis C virus genome.- Hepatitis C virus polyprotein processing.- Processing mechanisms of nonstructural proteins of hepatitis C virus.- Immunoelectron microscopic localization of processed core protein of hepatitis C virus in COS cells.- The physical state of the negative strand of hepatitis C virus RNA in serum.- Immunology and pathogenesis.- 1. Immunopathogenesis.- Cellular immune responses to hepatitis viruses: summary of a Specialty Session.- Studies of cytotoxic T lymphocyte activity in tamarins with acute hepatitis A virus infection.- Adoptive transfer of immunity to hepatitis B through bone marrow transplantation from immunized donors.- Peptide recognition and competition, T cell receptor usage, and HLA restriction elements of T cell clones specific to a determinant of hepatitis B virus core and e antigens in chronic type B hepatitis.- A method to detect hepatitis B virus-specific cytotoxic T lymphocytes in patients with acute and chronic HBV infection.- The role of the cytotoxic T lymphocytes response in hepatitis B virus immunobiology and path