High Altitude Sickness - Solutions from Genomics, Proteomics and Antioxidant Interventions (Paperback, 2022)

Chapter 1_Hypoxia, Hypoxia accelmatization and Omics tools for assessment. -Chapter 1.1. General Description of various types of hypoxia. -Chapter 1.2.Hypobaric hypoxia in particular and physiological changes. -Chapter 1.3. Hypoxia acclemetization and its molecular framework. -Chapter 1.4. Classical tools of study. -Chapter 1.5.Omics as an emerging tool for revisiting hypoxia. -Chapter 2_High altitude sickness: Introduction.- Chapter 2.1. High altitudes and hypoxia as primary environmental stressor. -Chapter 2.2. Altered physiological response at high altitude. -Chapter 2.3. High allied sickness - milder effects. -Chapter. 2.4. Hypobaric hypoxia and brain, HACE and related cognitive disorders. -Chapter 2.5. Hypobaric hypoxia and Lungs, HAPE and related disorders. -Chapter 2.6. Hypobaric hypoxia and Muscles and related disorders. -Chapter 2.7. Hypobaric hypoxia and Cardiovascular system, Thrombosis, embolism and related disorders. -Chapter 2.8. Integration of various physiological changes and systemic indicators. -Chapter 3_Oxidative stress and proteomic alteration in high altitude. -Chapter 3.1. Mechanism of radical generation in high altitude - effect of oxidative stress. -Chapter 3.2. Oxidative stress during hypoxia. -Chapter 3.3. Mechanism of proteomic alterations in high altitude. -Chapter 3.4. Altered hemostasis in hypoxia.- Chapter 4_Current problems in diagnosis and treatment of high altitude sickness.- Chapter 4.1. Problem of detecting susceptibility. -Chapter 4.2. No available non-invasive technique. -Chapter 4.3. No effective medical intervention except decent. -Chapter 5_Proteomics as potential tool for biomarker discovery. -Chapter 5.1. How proteomics is useful? -Chapter 5.2. Common proteomics tools. -Chapter 5.3. Advanced/emerging proteomics techniques. -Chapter 6_Serum/Plasma proteomics for high altitude related biomarker discovery. -Chapter 6.1.Serum proteomics in animal models of hypoxia. -Chapter 6.2. Serum proteomics in human subjects of hypoxia. -Chapter 6.3. Potential /candidate biomarkers for diagnostic /therapeutic roles. -Chapter 7_Saliva? proteomics for non-invasive application. -Chapter 7.1.Importance of saliva as a potential sample. -Chapter 7.2. Less known biomarkers of saliva. -Chapter 7.3. Emerging trends. -Chapter 8_Genomics and Metabolomics insight into hypoxia marker identification. -Chapter 8.1. Genomic fingerprints of high altitude sickness and susceptibility. -Chapter 8.2.Polymorphisms as a potential tool for high altitude adaptation. -Chapter 8.3.Trends in Metabolomics as emerging tool. -Chapter 9_Antioxidant therapies for high altitude sickness. -Chapter 9.1. Conventional phytoextracts. -Chapter 9.2. Novel nanomedicine. -Chapter 9.3. Other antioxidants and metabolic regulators.