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· 분류 : 외국도서 > 과학/수학/생태 > 과학 > 생명과학 > 유전학/유전체학
· ISBN : 9780470195147
· 쪽수 : 480쪽
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Preface xiii
Contributors xvii
Part I Evolution of Life.
1. Evolutionary Genomics Leads the Way 3
David Penny and Lesley J. Collins
1.1 Introduction 3
1.2 Evolution and the Power of Genomes 4
1.3 The Problem of Deep Phylogeny and "The Tree" 5
1.4 Fred, the Last Common Ancestor of Modern Eukaryotes 7
1.5 Eukaryote Origins: Continuity from the RNAWorld? 10
1.6 Minimal Genomes and Reductive Evolution 12
1.7 Evolutionary Genomics for the Future 13
2. Current Approaches to Phylogenomic Reconstruction 17
Denis Baurain and Herve Philippe
2.1 Phylogenomics and Supermatrices 17
2.2 Phylogenetic Signal Versus Nonphylogenetic Signal 19
2.3 Probabilistic Models and Nonphylogenetic Signal 22
2.4 Reduction of Nonphylogenetic Signal Under Fixed Models 28
2.5 CAT Model 31
2.6 Case Study: Cambrian Explosion 33
2.7 Conclusion 35
3. The Universal Tree of Life and the Last Universal Cellular Ancestor: Revolution and Counterrevolutions 43
Patrick Forterre
3.1 Introduction 43
3.2 The Woesian Revolution 45
3.3 A Rampant "Prokaryotic" Counterrevolution 47
3.4 How to Polarize Characters Without a Robust Root? 50
3.5 The Hidden Root: When the Weather Became Cloudy 51
3.6 LUCA and Its Companions 54
3.7 The Problem of Horizontal Gene Transfer and Ancient Phylogenies: Trees Versus Gene Webs 54
3.8 The Nature of the RNAWorld 55
3.9 The DNA Replication Paradox and the Nature of LUCA 56
3.10 When Viruses Find Their Way into the Universal Tree of Life 58
3.11 Future Directions 59
4. Eukaryote Evolution: The Importance of the Stem Group 63
Anthony M. Poole
4.1 Introduction 63
4.2 Interpreting Trees 68
4.3 Moving Beyond the Deep Roots of Eukaryotes 70
4.4 Concluding Remarks 76
5. The Role of Information in Evolutionary Genomics of Bacteria 81
Antoine Danchin and Agnieszka Sekowska
5.1 Introduction 81
5.2 Revisiting Information 83
5.3 Ubiquitous Functions for Life 84
5.4 The Cenome and the Paleome 87
5.5 Functions Corresponding to Nonessential Persistent Genes 89
5.6 A Ubiquitous Information-Gaining Process: Making a Young Organism from an Aged One 89
5.7 Provisional Conclusion 91
6. Evolutionary Genomics of Yeasts 95
Bernard Dujon
6.1 Introduction 95
6.2 A Brief History of Hemiascomycetous Yeast Genomics 96
6.3 The Scientific Attractiveness of S. cerevisiae 98
6.4 Evolutionary Genomics of Hemiascomycetes 104
6.5 Surprises 111
6.6 What Next? 113
Part II Evolution of Molecular Repertoires.
7. Genotypes and Phenotypes in the Evolution of Molecules 123
Peter Schuster
7.1 The Landscape Paradigm 123
7.2 Molecular Phenotypes 125
7.3 The RNA Model 132
7.4 Conclusions and Outlook 148
8. Genome Evolution Studied Through Protein Structure 153
Philip E. Bourne, Kristine Briedis, Christopher Dupont, Ruben Valas, and Song Yang
8.1 Introduction 153
8.2 Structural Granularity and Its Implications 156
8.3 Protein Domains in the Study of Genome Rearrangements 158
8.4 Protein Domain Gain and Loss 160
8.5 And in the Beginning . . . 161
8.6 But Let Us Not Forget the Influence of the Environment 161
8.7 Conclusions 162
9. Chromosomal Rearrangements in Evolution 165
Hao Zhao and Guillaume Bourque
9.1 Introduction 165
9.2 Genome Representation 166
9.3 Constructing Genome Permutations from Sequence Data 167
9.4 Genomic Distances 168
9.5 Reconstruction of Ancestors and Evolutionary Scenarios 174
9.6 Recent Applications on Large Genomes 177
9.7 Challenges and Promising New Approaches 178
10. Molecular Structure and Evolution of Genomes 183
Todd A. Castoe, A. P. Jason de Koning, and David D. Pollock
10.1 Introduction 183
10.2 Overview of Considerations in Studying Protein Evolution 184
10.3 Function and Evolutionary Genomics 186
10.4 Integrating Inferences to Detect and Interpret Adaptation: An Example with Snake Metabolic Proteins 194
10.5 Conclusion 200
11. The Evolution of Protein Material Costs 203
Jason G. Bragg and Andreas Wagner
11.1 Introduction 203
11.2 Protein Material Costs 204
11.3 An Example: Proteomic Sulfur Sparing 205
11.4 Episodic Nutrient Scarcity Can Shape Protein Material Costs 205
11.5 Highly Expressed Gene Products Often Exhibit Reduced Material Costs 206
11.6 Material Costs and the Evolution of Genomes 207
11.7 Material Costs and Other Costs of Making Proteins 208
11.8 Conclusions 209
12. Protein Domains as Evolutionary Units 213
Andrew D. Moore and Erich Bornberg-Bauer
12.1 Modular Protein Evolution 213
12.2 Domain-Based Homology Identification 215
12.3 Domains in Genomics and Proteomics 222
12.4 The Coverage Problem 225
12.5 Conclusion 227
13. Domain Family Analyses to Understand Protein Function Evolution 231
Adam James Reid, Sarah Addou, Robert Rentzsch, Juan Ranea, and Christine Orengo
13.1 Introduction 231
13.2 Universal Domain Structure Families Identified in the Last Universal Common Ancestor 232
13.3 Some Domain Families Recur More Frequently and Are Structurally Very Diverse 234
13.4 Correlation of Structural Diversity in Superfamilies with Functional Diversity 234
13.5 To What Extent Does Function Vary Between Homologous? 238
13.6 HowSafely Can Function Be Inherited Between Homologues? 245
13.7 HowAre Domain Families Distributed in Protein Complexes? 247
14. Noncoding RNA 251
Alexander Donath, Sven Findeib, Jana Hertel, Manja Marz, Wolfgang Otto, Christine Schulz, Peter F. Stadler, and Stefan Wirth
14.1 Introduction 251
14.2 Ancient RNAs 254
14.3 Domain-Specific RNAs 259
14.4 Conserved ncRNAs with Limited Distribution 267
14.5 ncRNAs from Repeats and Pseudogenes 276
14.6 mRNA-like ncRNAs 277
14.7 RNAs with Dual Functions 281
14.8 Concluding Remarks 282
15. Evolutionary Genomics of microRNAs and Their Relatives 295
Andrea Tanzer, Markus Riester, Jana Hertel, Clara Isabel Bermudez-Santana, Jan Gorodkin, Ivo L. Hofacker, and Peter F. Stadler
15.1 Introduction 295
15.2 The Small RNA Zoo 296
15.3 Small RNA Biogenesis 298
15.4 Computational microRNA Prediction 302
15.5 microRNA Targets 304
15.6 Evolution of microRNAs 307
15.7 Origin(s) of microRNA Families 313
15.8 Genomic Organization 316
15.9 Summary and Outlook 320
16. Phylogenetic Utility of RNA Structure: Evolution’s Arrow and Emergence of Early Biochemistry and Diversified Life 329
Feng-Jie Sun, Ajith Harish, and Gustavo Caetano-Anolles
16.1 Introduction 329
16.2 Structural Characters and Derived Phylogenetic Trees 333
16.3 Applications 344
16.4 Conclusions 353
Part III Evolution of Biological Networks.
17. A Hitchhiker’s Guide to Evolving Networks 363
Charles G. Kurland and Otto G. Berg
17.1 Introduction 363
17.2 Phylogenetic Continuities, Biological Coherence 367
17.3 Nested Structural Networks 371
17.4 Optimal Networks 374
17.5 The Emperor's BLAST Search Revisited 381
17.6 Will the Real Missing Link Please Stand Up? 388
17.7 All's Well 389
18. Evolution of Metabolic Networks 397
Eivind Almaas
18.1 Introduction 397
18.2 Metabolic Network Properties 398
18.3 Network Models For Metabolic Evolution 403
18.4 Dynamic Models Of Genome-Level Metabolic Function 407
19. Single-Gene and Whole-Genome Duplications and the Evolution of Protein–Protein Interaction Networks 413
Grigoris Amoutzias and Yves Van de Peer
19.1 Introduction 413
19.2 Evolution of PINs 414
19.3 Single-Gene Duplications 416
19.4 Whole-Genome Duplications 416
19.5 Diploidization Phase 416
19.6 Dosage Balance Hypothesis 417
19.7 Types of Interactions 417
19.8 WGDs, Transient Interactions, and Organismal Complexity 418
19.9 Studies on PPIs of Ohnologues 419
19.10 Concerns About the Methods of Analysis and the Quality of the Data 420
19.11 The Importance of Medium-Scale Studies: the Case of Dimerization 422
19.12 Evolution of Dimerization Networks 424
19.13 Conclusions 426
20. Modularity and Dissipation in Evolution of Macromolecular Structures, Functions, and Networks 431
Gustavo Caetano-Anolles, Liudmila Yafremava, and Jay E. Mittenthal
20.1 Introduction 431
20.2 Biological Structure as an Emergent Property of Dissipative Systems 432
20.3 Information and Its Dissipation 435
20.4 Time, Thermodynamic Irreversibility, and Growth of Order in the Universe 437
20.5 Information Dissipation and Modularity Pervade Structure in Biology 440
20.6 Modularity and Dissipation in Protein Evolution 443
20.7 Conclusions 447
Acknowledgments 448
References 448
Index 451
