Medicinal Chemistry (Paperback)

PART I: Drug Discovery and Development

1. Historical Perspective and Overview of Drug Discovery

2. Drug discovery: Hit and Lead Discovery

3. Drug Discovery: Optimization of Lead Properties

PART II: Classes of Drug Targets

4. Medicinal Chemistry Strategies Used in Lead Optimization

5. The Process of Developing a Drug from an Optimized Lead

6. Receptors as Drug Targets

7. Enzymes as Drug Targets

8. Protein-Protein Interactions and Lipids as Drug Targets

9. DNA and RNA as Drug Targets

PART III: Selected Therapeutic Areas

10. Anti-Cancer Drugs

11. Infectious Diseases I: Antiviral and Antifungal Drugs

12. Infectious Diseases II: Antibacterial and Antiparasitic Drugs

13. Drugs Acting on the CNS