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· 제목 : Adaptive Design Methods in Clinical Trials (Paperback, 2 ed) 
· 분류 : 외국도서 > 의학 > 연구
· ISBN : 9781032477602
· 쪽수 : 374쪽
· 분류 : 외국도서 > 의학 > 연구
· ISBN : 9781032477602
· 쪽수 : 374쪽
목차
Introduction. Protocol Amendment. Adaptive Randomization. Adaptive Hypotheses. Adaptive Dose-Escalation Trials. Adaptive Group Sequential Design. Statistical Tests for Seamless Adaptive Designs. Adaptive Sample Size Adjustment. Two-Stage Adaptive Design. Adaptive Treatment Switching. Bayesian Approach. Biomarker Adaptive Trials. Target Clinical Trials. Sample Size and Power Estimation. Clinical Trial Simulation. Regulatory Perspectives ? A Review of FDA Draft Guidance. Case Studies. Bibliography. Subject Index.
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