Getting to Good: Research Integrity in the Biomedical Sciences (Hardcover, 2018)

PREFACE CONTENTS CHAPTER 1. METHODOLOGY Arthur L. Caplan 1.1. Why Most Published Research Findings Are False John P. A. Ioannidis 1.2 The Controversy Surrounding Bone Morphogenetic Proteins in the Spine: A Review of Current Research Joshua W. Hustedt and Daniel J. Blizzard 1.3. Research Integrity and Everyday Practice of Science Frederick Grinnell 1.4. Lessons from the Infuse Trials: Do We Need a Classification of Bias in Scientific Publications and Editorials? Sohaib Hashmi, Mohamed Noureldin, and Safdar N. Khan CHAPTER 2. POLICY Arthur L. Caplan 2.1. In Retrospect: Science-The Endless Frontier Roger Pielke Jr 2.2. Publish or Perish Culture Encourages Scientists to Cut Corners Virginia Barbour 2.3. "Something of an Adventure": Postwar NIH Research Ethos and the Guatemala STD Experiments Kayte Spector-Bagdady and Paul A. Lombardo 2.4. Perverse Incentives Paula Stephen 2.5. Flint Water Crisis Yields Hard Lessons in Science and Ethics Katie L. Burke CHAPTER 3. REPRODUCIBILITY Arthur L. Caplan 3.1. What Does Research Reproducibility Mean? Steven N. Goodman, Daniele Fanelli, and John P.A. Ioannidis 3.2. Limited Reproducibility of Research Findings: Implications for the Welfare of Research Participants and Considerations for Institutional Review Boards Barbara K. Redman and Arthur L. Caplan 3.3. Quality Time Monya Baker CHAPTER 4. HUMAN SUBJECTS PROTECTION Arthur L. Caplan 4.1. A Scoping Review of Empirical Research Relating to Quality and Effectiveness of Research Ethics Review Stuart G. Nicholls, Tavis P. Hayes, Jamie C. Brehaut, Michael McDonald, Charles Weijer, Raphael Saginur, and Dean Fergusson 4.2. Pharmaceuticalisation and Ethical Review in South Asia: Issues of Scope and Authority for Practitioners and Policy Makers Bob Simpson, Rekha Khatri, Deapica Ravindran, Tharindi Udalagama 4.3 . Understanding the Functions and Operations of Data Monitoring Committees: Survey and Focus Group Findings Karim A Calis, Patrick Archdeacon, Raymond Bain, David DeMets, Miriam Donohue, M Khair Elzarrad, Annemarie Forrest, John McEachern, Michael J Pencina, Jane Perlmutter, and Roger J Lewis 4.4. Women and Fetuses First? Women and Fetuses First? An Ethical Case for Giving Priority in Clinical Research Testing of Zika Vaccines to Pregnant Women Kelly McBride Folkers and Arthur L. Caplan 4.5. Rethinking the Belmont Report? Phoebe Friesen, Lisa Kearns, Barbara Redman, and Arthur L. Caplan CHAPTER 5. RESPONSIBLE AUTHORSHIP Arthur L. Caplan 5.1. The Problem of Publication-Pollution Denialism Arthur L. Caplan 5.2. Addressing Research Misconduct and Detrimental Research Practices: Current Knowledge and Issues National Academy of Sciences 5.3. Exploring New Approaches National Academy of Sciences 5.4. A Systematic Review of Research on the Meaning, Ethics and Practices of Authorship across Scholarly Disciplines Ana Marusic, Lana Bosnjak, and Ana Jeroncic 5.5. The Disposable Author: How Pharmaceutical Marketing is Embraced within Medicine's Scholarly Literature Alastair Matheson 5.6. Authorship Inflation in Medical Publications Gaurie Tilak, Vinay Prasad, Annupam B. Jena CHAPTER 6. MENTOR-MENTEE RESPONSIBILITIES AND RELATIONSHIPS Arthur L. Caplan 6.1. Closing the Barn Door: Coping with Findings of Research Misconduct by Trainees in the Biomedical Sciences Barbara K. Redman and Arthur L. Caplan 6.2. Mentoring and Research Misconduct: Analysis of Research Mentoring in Closed ORI Cases David E. Wright, Sandra L. Titus, and Jered B. Cornelison 6.3. Mentorship Matters for the Biomedical Workforce Sally J. Rockey 6.4. Professional Responsibility C.K. Gunsalus 6.5. All You Need is Mentorship Robert A. Weinberg, Maya Schuldiner, Hong Wu, Beth Steven