Group B Coxsackieviruses (Hardcover, 2008)

Section 1: CVB Genetics.- Coxsackieviruses and quasispecies theory: evolution of enteroviruses.- Comparative genomics of the coxsackie B viruses and related enteroviruses.- Group B coxsackievirus virulence.- Section 2: CVB Entry and Replication.- The coxsackievirus and adenovirus receptor (CAR).- Coxsackievirus B RNA replication: Lessons from poliovirus.- CVB translation: Lessons from the polioviruses.- Preferential coxsackievirus replication in proliferating/activated cells: implications for virus tropism, persistence, and pathogenesis.- Section 3 Host-Virus Interaction.- The impact of CVB3 infection on host cell biology.- Host immune responses to coxsackievirus B3.- Pediatric group B coxsackievirus infections.- Pancreas.- CVB-induced pancreatitis and alterations in gene expression.- The CVB and etiology of type 1 diabetes.- Heart.- Persistent coxsackievirus infection: Enterovirus persistence in chronic myocarditis and dilated cardiomyopathy.- Autoimmunity in coxsackievirus infection.- CVB infection and mechanisms of viral cardiomyopathy.- Subject index.