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· 제목 : Antibacterial Drug Discovery to Combat MDR: Natural Compounds, Nanotechnology and Novel Synthetic Sources (Hardcover, 2019)
· 분류 : 외국도서 > 의학 > 미생물학
· ISBN : 9789811398704
· 쪽수 : 680쪽
· 출판일 : 2019-11-20
· 분류 : 외국도서 > 의학 > 미생물학
· ISBN : 9789811398704
· 쪽수 : 680쪽
· 출판일 : 2019-11-20
목차
Section A: Problems associated with current antimicrobial therapy
1. Antibacterial drug discovery : perspective insights
2. Emergence and spread of multidrug resistance in ocular pathogens
3. Problematic groups of MDR bacteria and their resistance mechanisms
4. Biofilms in relation to enhanced drug resistance and persistence infection: challenges in chemotherapy
5. Environmental MDR a potential threat to human health and antimicrobial therapy
6. Impediments to discovery of new antimicrobials with new modes of action
7. Developing in vivo infection models with MDR pathogens for evaluating compound efficacy
Section B: New antibiotic drug discovery approaches and progress
8. Classical to improved microbial screening approaches for antibacterial drug discovery9. Endophytes: a hidden treasure of novel antimicrobial metabolites
10. New molecular drug targets: potential for developing novel antibacterials against MDR bacteria
11. Bio-synthetic gene clusters associated with marine sponge and with bacterial dwelling in marine sponges
12. Insilico molecular modelling for drug screening
bioinformatics and chemoinformatics: key technologies in the drug discovery process
13. Computational Approaches in relation to antibacterial drug discovery
14. Efflux pump inhibitors and their role in reversal of drug resistance
15. Medicinal plants as reservoir of new structure for anti-infective compounds
16. Antibacterial essential oils: Potential application in bacterial disease management.
17. Metagenomic approach to explore soil resistome.
18. Marinemicrobes as promising source of new leads as antibacterials: Current progress and prospects
Section C:Alternative antibiotic resistance treatment strategy
19. Role of pre and probiotics in protection from pathogenic bacteria
20. Enhancing antibiotic efficacy through synergistic approach
21. Reviving old antibiotics
22. Targeted Delivery of antibiotics using polymeric particles to combat TB resistance
23. Bacteriophages in pathogenic bacterial control: prospects and limitation.
24. Inhibition of Quorum sensing; prospects in disease control
25. Pathogenic Biofilm eradication strategies in combating bacterial infection
Section D:Nanomaterials as antibacterial drug: potentials and prospects
26. Nanomedicine /Nanoemulsion in increasing drug availability27. Nanoparticle as new emerging antibacterials: potential and limitation
28. Antibiofilm and antivirulence action of nanopartciles
29. Nanoparticle-based drug delivery systems: promising approaches against bacterial infections
30. Green synthesis of metal nanoparticles: characterization and their antibacterial efficacy
31. Protein and Peptide Nanoparticles for antibacterial Drug Delivery
