Handbook of the Biology of Aging (Hardcover, 6th)

HANDBOOK OF THE BIOLOGY OF AGING, 6e

Edited by Edward J. Masoro and Steve Austad

Section I: Conceptual and Technical Issues

Chapter 1
Reliability Theory of Aging and Longevity
Leonid A. Gavrilov and Natalia S. Gavrilova

Chapter 2 - Are Age-Associated Diseases an Integral Part of Aging?
Edward J. Masoro

Chapter 3 - Dietary Restriction, Hormesis and Small Molecule Mimetics
David A. Sinclair and Konrad T. Howitz

Chapter 4 - Hematopoietic Stem Cells, Aging, and Cancer
Deborah Bell and Gary Van Zant

Chapter 5 - Mitochondria: A Critical Role in Aging
Tamara Golden, Karl Morten, Felicity Johnson, Enrique Samper, and Simon Melov

Chapter 6 - P53 and Mouse Aging Models
Cathy Gatza, George Hinkal, Lynette Moore, Melissa Dumble, and Lawrence A. Donehower

Chapter 7 - Complex Genetic Architecture of Drosophila Longevity
Trudy Mackay, Natalia V. Roshina, Jeff W. Leips, and Elena G. Pasyukova

Chapter 8 - Evolutionary Biology of Aging: Future Directions
Daniel Promislow, Ken Fedorka, and Joep Burger

Chapter 9 - Senescence in Wild Populations of Mammals and Birds
Anja Brunet-Rossini and Steven N. Austad

Chapter 10 - Biodemography of Aging and Age-Specific Mortality in Drosophila melanogaster
James Curtsinger, Natalia S. Gavrilova, and Leonid A. Gavrilov

Chapter 11 - Microarray Analysis of Gene Expression Changes in Aging
F. Noel Hudson, Matt Kaeberlein, Nancy Linford, David Pritchard, Richard Beyer, and Peter S. Rabinovitch

Chapter 12 - Computer Modeling in the Study of Aging
Thomas Kirkwood, Richard Boys, Colin Gillespie, Carole Procter, Daryl Shanley, and Darren Wilkenson

Section II: Non-Mammalian Models

Chapter 13 - Dissecting the Processes of Aging Using the Nematode Caenorhabditis elegans
Thomas E. Johnson, Samuel T. Henderson, Shane Rea

Chapter 14 - Genetic Manipulation of Life span in Drosophila. Melanogaster
Daniel Ford and John Tower

Chapter 15 - Juvenile and Steroid Hormones in Drosophila melanogaster Longevity
Meng-Ping Tu, Thomas Flatt,, Marc Tatar

Chapter 16 - A Critical Evaluation of Nonmammalian Models for Aging Research
Steven N. Austad, Andrej Podlutsky

Section III: Mammalian Models

Chapter 17 - Differential Aging Among Skeletal Muscles
Roger J. M. McCarter

Chapter 18 - Aging, Body Fat, and Carbohydrate Metabolism
Marielisa Rincon, Radhika Muzumdar, and Nir Barzilai

Chapter 19 - Growth and Aging: Why do Big Dogs Die young?
Richard Miller and Steven N. Austad

Chapter 20 - Growth Hormone, Insulin-Like Growth Factor-1 and the Biology of Aging
Christy S. Carter and William E. Sonntag

Chapter 21 - Aging of the Female Reproductive System
Phyllis Wise