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· 분류 : 외국도서 > 과학/수학/생태 > 과학 > 생명과학 > 분자 생물학
· ISBN : 9780125466615
· 쪽수 : 488쪽
· 출판일 : 2005-06-06
목차
Chapter 1: Molecular Diagnostics: Past, Present, and Future
Section I: Molecular Diagnostic Technology
Chapter 2: Allele-Specific Mutation Detection by PCR-ARMS and PCR-ASO
Chapter 3: Competitive Oligopriming
Chapter 4: Oligonucleotide Ligation Assays for the Diagnosis of Inherited Diseases
Chapter 5: Enzymatic and Chemical Cleavage Methods to Identify Genetic Variation
Chapter 6: Mutation Detection by Single Strand Conformation Polymorphism and Heteroduplex Analysis
Chapter 7: Capillary Electrophoresis
Chapter 8: Temperature and Denaturing Gradient Gel Electrophoresis
Chapter 9: Two-Dimensional Gene Scanning
Chapter 10: Real-Time Polymerase Chain Reaction
Chapter 11: Pyrosequencing
Chapter 12: Molecular Cytogenetics in Molecular Diagnostics
Chapter 13: Detection of Genomic Duplications and Deletions
Chapter 14: Analysis of Human Splicing Defects Using Hybrid Minigenes
Chapter 15: DNA Microarrays and Genetic Testing
Chapter 16: Human Genome Microarray in Biomedical Applications
Chapter 17: Use of High Throughput Mass Spectrographic Methods to Identify Disease Processes
Chapter 18: The Application of Proteomics to Disease Diagnostics
Section II: Applications of Molecular Diagnostics and Related Issues
Chapter 19: Identification of Genetically Modified Organisms
Chapter 20: Pharmacogenetics and Pharmacogenomics: Impact on Drug Discovery and Development
Chapter 21: Molecular Diagnostic Applications in Forensic Science
Chapter 22: Molecular Diagnostics and Comparative Genomics in Clinical Microbiology
Chapter 23: Preimplantation Genetic Diagnosis
Chapter 24: Genetic Monitoring of Laboratory Animals
Chapter 25: The Use of Locus-Specific Databases in Molecular Diagnostics
Chapter 26: Safety Analysis in Retroviral Gene Therapy: Identifying Virus Integration Sites in Gene-Modified Cells
Chapter 27: Automated DNA Hybridization and Detection
Chapter 28: The Use of Microelectronic-Based Techniques in Molecular Diagnostic Assays
Chapter 29: Miniaturization Technologies for Molecular Diagnostics
Chapter 30: Human Gene Patents and Genetic Testing
Chapter 31: Genetic Counselling and Ethics in Molecular Diagnostics
Chapter 32: Genetic Testing and Psychology
Chapter 33: Safety in Biomedical and Other Laboratories
Chapter 34: Quality Management in the Laboratory