Comprehensive Enzyme Kinetics (Hardcover)

1. Introduction.- 2. Chemical kinetics.- 3. Kinetics of monosubstrate reactions.- 4. Derivations of rate equations.- 5. Linear inhibition.- 6. Hyperbolic and parabolic inhibition.- 7. Enzyme activation.- 8. Kinetics of rapid equilibrium bisubstrate reactions.- 9. Steady state kinetics of bisubstrate reactions.- 10. Kinetic analysis of bisubstrate mechanisms.- 11. Substrate inhibition and mixed dead-end and product inhibition.- 12. Kinetics of trisubstrate reactions.- 13. Cooperative and allosteric effects.- 14. The pH dependence of enzyme catalysis.- 15. Effects of temperature on enzyme reactions.- 16. Isotope exchange.- 17. Solvent and kinetic isotope effects.- 18. Statistical analysis of initial rate and binding data.- Subject index.