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· 분류 : 외국도서 > 과학/수학/생태 > 과학 > 생명과학 > 미생물학
· ISBN : 9780387397146
· 쪽수 : 460쪽
· 출판일 : 2007-05-03
목차
Introduction: Heat Shock Proteins-From Drosophila Stress Proteins to Mediators of Human Disease.- Introduction: Heat Shock Proteins-From Drosophila Stress Proteins to Mediators of Human Disease.- Stress Response and Molecular Chaperones.- Biology of the Heat Shock Response and Stress Conditioning.- Bacterial Stress Sensors.- Unfolded Protein Response: Contributions to Development and Disease.- Molecular Mechanisms of Stress Protein Expression.- Genetic Models of HSF Function.- HSF1 and HSP Gene Regulation.- Cellular Stress Proteins.- Small Heat Shock Proteins in Physiological and Stress-Related Processes.- Large Mammalian hsp70 Family Proteins, hsp110 and grp170, and Their Roles in Biology and Cancer Therapy.- Molecular Chaperones and Protein Folding.- Regulation of Hsp70 Function: Hsp40 Co-Chaperones and Nucleotide Exchange Factors.- Protein Disassembly by Hsp40-Hsp70.- Mammalian HSP40/DnaJ Chaperone Proteins in Cytosol.- Role of Molecular Chaperones in Cell Regulation.- FKBP Co-Chaperones in Steroid Receptor Complexes.- Up and Down Regulation of the Stress Response by the Co-Chaperone Ubiquitin Ligase CHIP.- Role of Cdc37 in Protein Kinase Folding.- Intracellular and Extracellular Stress Proteins in Human Disease.- Targeting Hsp90 in Cancer and Neurodegenerative Disease.- gp96 and Tumor Immunity.- Immunoregulatory Activities of Extracellular Stress Proteins.- Heat Shock Proteins and Neurodegenerative Diseases.- Heat Shock Proteins in the Progression of Cancer.














