Systems Biology of Cell Signaling: Recurring Themes and Quantitative Models (Paperback)

Preface.? Acknowledgements.? 1. Introduction.? 2. Receptors I: Monomeric Receptors and Ligands.? 3. Receptors II: Multimeric Receptors and Cooperativity.??4. Downstream Signaling I: Stoichiometric Regulation.? 5. Downstream Signaling II: Covalent Modification.? 6. Downstream Signaling III: Regulated Production or Destruction.? 7. Cascades and Amplification.? 8. Bistability I: Systems with One-Time Dependent Variable.? 9. Bistability II: Systems with Two Time-Dependent Variables.? 10. Transcritical Bifurcations in Phase Separation and Infectious Disease.? 11. Negative Feedback I: Stability and Speed.? 12. Negative Feedback II: Adaption.? 13. Adaption II: Incoherent Feed-Forward Regulation and State-Dependent Activation.? 14. Negative Feedback 3: Oscillations.? 15. Relaxation Oscillators.? 16. Excitability.? 17. Wrap-Up.? Glossary.? Index.??