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· 분류 : 외국도서 > 과학/수학/생태 > 과학 > 화학 > 유기화학
· ISBN : 9781071617540
· 쪽수 : 632쪽
· 출판일 : 2022-11-13
목차
PART I: Introduction, selection, mechanisms.
1. Cell-penetrating peptides
Matja? Zorko and Ulo Langel
2. Shuttling homeoproteins and their biological significance
Alain Prochiantz and Ariel Di Nardo
3. Artificial evolutionary optimization process to improve the functionality of CPPs
Niels Rockendorf, Katrin Ramaker, and Andreas Frey
4. In silico design of chemically modified cell penetrating peptides
Vinod Kumar, Gajendra Pal Singh Raghava
5. Synthetic Molecular Evolution of Cell Penetrating Peptides
William C. Wimley
6. A native CPP from rattlesnake with therapeutic and theranostic properties
Lucas C. Porta, Joana D’Arc Campeiro, and Mirian A. F. Hayashi
7. Synthesis of cell-penetrating peptide coated silica nanoparticles and their physicochemical and biological characterization
Isabel Gessner, Annika Klimpel and Ines Neundorf
8. Enhancing the therapeutic potential of extracellular vesicles using peptide technology
Carla Martin-Perez, Mariana Conceicao, Richard Raz, Matthew J. A. Wood, and Thomas C. Roberts
9. Challenges and methods for the study of CPP translocation mechanisms
Astrid Walrant, Francoise Illien, Sandrine Sagan, and Nicolas Rodriguez
10. Membrane molecular interactions and induced structures of CPPs
Fatemeh Madani and Astrid Graslund
11. A single GUV method for revealing the action of cell-penetrating peptides in biomembranes
Md. Mizanur Rahman Moghal, Madhabi Lata Shuma, Md. Zahidul Islam, and Masahito Yamazaki
12. Methods for Small-Angle Scattering Measurements on Peptiplexes of DNA with Cell-Penetrating Peptides
Emerson R.Silva, Lucas R. Mello, and Ian Hamley
13. Imaging CPP delivery mechanisms of oligonucleotides
Najoua El Boujnouni, Alexander H. van Asbeck, Jurgen Dieker, Derick G. Wansink, and Roland Brock
14. Quantitative subcellular analysis of cyclic cell-penetrating peptide EJP18 in non-adherent cells
Edward J. Sayers, Victoria L. Barlow, Yu-Hsuan Tsai, and Arwyn T. Jones
15. PepFect14: signaling and transfection
Luca Falato, Maxime Gestin, and Ulo Langel16. Utilisation of cell-penetrating peptides for in vivo delivery of bioactive cargo ? the effect of nanoparticle formulation
Piret Arukuusk, Heleri Heike Hark, and Ulo Langel
Part II: Delivery of proteins and protein mimics.
17. Protein delivery by PTDs/CPPs
Caroline Palm-Apergi and Steve F. Dowdy
18. Protein Delivery to Cytosol by Cell-Penetrating Peptide Bearing a Tandem Repeat Penetration-Accelerating Sequence
Akiko Okuda and Shiroh Futaki
19.Recombinant transcription factors (TFs) fused to ZEBRA minimal transduction domain (MD) for modulation of mRNA transcripts.
Benjamin Caulier, Jean-Luc Lenormand, and David Laurin
20. Protein mimicry and the design of bioactive cell penetrating peptides: The genesis of STOPSPERM bioportides
John Howl*, Joana Vieira Silva,, Margarida Fardilha, and Sarah Jones
21. Lipopeptide pepducins as therapeutic agents
Emily Michael, Lidija Covic, and Athan Kuliopulos
22. Delivery of Antibiotics by Cell-Penetrating Peptides to Kill Intracellular Pathogens
Christian Ruter
23. CPP applications in immune modulation and disease therapy
Ja-Hyun Koo, Won-Ju Kim, and Je-Min Choi
Part III: Targeting
24. Cell-penetrating peptides as carriers for transepithelial drug delivery
Danai Anastasia Panou, Ragna Guldsmed Diedrichsen, Mie Kristensen, and Hanne Mørck Nielsen
25. New tools for streamlined in vivo homing peptide identification
Kristina Po?nograjeva, Karlis Pleiko, Maarja Haugas, and Tambet Teesalu
26. Tumor targeting as new therapeutic approach
Eric Savier, Pierre Tuffery, Heriberto Bruzzoni-Giovannelli and Angelita Rebollo
27. Mitochondrial Targeting Probes, drug conjugates and gene therapeutics
Carmine Pasquale Cerrato, Tove Kivijarvi, and Ulo Langel
28. Novel brain penetrating single chain antibodies directed against 3RTau for the Treatment of Alzheimer’s Disease and related Dementias
Brian Spencer, Robert A. Rissman, Cassia Overk, and Eliezer Masliah
29. Strategies for peptide-mediated cargo delivery to human smooth muscle cells
Leo Gurney, Steven C. Robson, Michele Sweeney, Arwyn T. Jones, and Michael J. Taggart
Part IV: Oligonucleotide delivery
30. Tips and Tools to Understand Direct Membrane Translocation of siRNA-Loaded WRAP-Based Nanoparticles.
Sebastien Deshayes, Karidia Konate, Eric Vives, and Prisca Boisguerin
31. Evaluating efficacy of peptide-delivered oligonucleotides using the severe Taiwanese SMA mouse model
Larissa Goli, Jessica Stoodley, Suzan Hammond, and Richard Raz
32. Development of CPP-based methods for delivery of miRNAs into the skin and airways - lessons from cell culture and mouse models
Anet Laanesoo, Kapilraj Periyasamy, Margus Pooga, and Ana Rebane
33. Endpoint and kinetic approaches for assessing transfection efficacy in mammalian cell culture
Ly Porosk, Jekaterina Nebogatova, Ilja Gaidut?ik, and Ulo Langel
34. Tissue analysis of lung-targeted delivery of siRNA and plasmid DNA
Kaido Kurrikoff, Birgit Vunk, and Ulo Langel
35. Improvement of transfection with PepFects by organic and inorganic components.
Moataz Dowaidar, Hani Nasser Abdelhamid, and Ulo Langel
36. DNA Transfer into Animal Cells Using Stearylated CPP Based Transfection Reagent
Kristi Kasemaa, Kaia Talts, Evelin Taht, Urve Toots, and Mart Ustav
37. Use of PepFect14 and siRNA for targeted gene silencing in human embryonic stem cells
Egle-Helene Ervin, Margus Pooga, and Toivo Maimets
38. CRISPR/Cas9 plasmid delivery through the CPP: PepFect14
Luca Falato, Birgit Vunk, and Ulo Langel
39. Applications of CPPs in genome editing of plants
Atta Soliman, John Laurie, Andriy Bilichak, and Alicja Ziemienowicz
40. Live Cell Genomics: Cell-specific transcriptome capture and exon-specific RNA binding protein isolation in live tissues and cells
Jaehee Lee and James Eberwine
