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· 분류 : 외국도서 > 과학/수학/생태 > 과학 > 생명과학 > 분자 생물학
· ISBN : 9781493984206
· 쪽수 : 303쪽
· 출판일 : 2018-08-03
목차
Part I: Introduction and Review
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1. ErbB Receptors and Cancer
??????????? Zhixiang Wang
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2. New Insights from Drosophila into the Regulation of EGFR Signaling
??????????? Nicholas Harden
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3. C. elegans Vulva Induction: An In Vivo Model to Study Epidermal Growth Factor Receptor Signaling and Trafficking
??????????? Kimberley Gauthier and Christian E. Rocheleau?
4. Targeting HER2 in Advanced Breast Cancer
??????????? Xiaofu Zhu and Anil Abraham Joy
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Part II: Classical Methods in the Studies of ErbB Receptor Signaling
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5. Methods to Investigate EGFR U
biquitination??????????? Alexia Conte and Sara Sigismund
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6. Dimerization Assessment of Epithelial Growth Factor Family of Receptor Tyrosine Kinases by Using Cross-Linking Reagent
??????????? Hamid Maadi, Babak Nami, and Zhixiang Wang
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7. Application of Immunofluorescence Staining to Study ErbB Family of Receptor Tyrosine Kinases
??????????? Babak N. Mollalou and Zhixiang Wang
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8. Activation of Endosome-Associated Inert EGF Receptor Following Internalization
??????????? Yi Wang, Sukhmani Billing, and Zhixiang Wang
?9. Two-Pulse Endosomal Stimulation of Receptor Tyrosine Kinases Induces Cell Proliferation
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nbsp;????????? Steven Pennock, Sukhmani Billing, Zhixiang Wang, and Yi Wang?
10. Study of EGFR Signalling/Endocytosis by Site-Directed Mutagenesis
??????????? Qian Wang and Zhixiang Wang
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11. Using Percoll Gradient Fractionation to Study the Endocytic Trafficking of the EGFR
??????????? Julie S. Gosney and Brian P. Ceresa
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12. Analysis of Epidermal Growth Factor Receptor-Induced Cell Motility by Wound Healing Assay
??????????? Junfeng Tong and Zhixiang Wang
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Part III: Recently Developed Methods in the Studies of ErbB Receptor Signaling
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13. Cell Cycle Synchronization of HeLa Cells to Assay EGFR Pathway A
ctivation ??????????? Ping Wee and Zhixiang Wang?
14. Analysis of Constitutive EGFR Signaling Regulating IRF3 Transcriptional Activity in Cancer Cells
??????????? Gao Guo, Ke Gong, and Amyn A. Habib
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15. Measurement of Epidermal Growth Factor Receptor-Derived Signals Within Plasma Membrane Clathrin Structures
??????????? Stefanie Lucarelli, Ralph Christian Delos Santos, and Costin N. Antonescu
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Part IV: Methods for Studying EGFR Signaling in Drosophila
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16. Studying Non-Proliferative Roles for Egfr Signaling in Tissue Morphogenesis Using Dorsal Closure of the Drosophila Embryo
??????????? Bruce Reed and Nicholas H
arden?
Part V: Methods Related to the Translational Research of ErbB Receptor Signaling
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17. Analysis of Epithelial-Mesenchymal Transition Induced by Overexpression of Twist
??????????? Jing-Wen Bai, Yong-Qu Zhang, Yao-Chen Li, and Guo-Jun Zhang
?18. Assessment of Specificity of an Adenovirus Targeted to HER3/4
??????????? Sheena H. MacLeod, Kyle G. Potts, Shyambabu Chaurasiya, and Mary M. Hitt
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19. Isolation of Human Mesenchymal Stem Cells for Studying ErbB Receptor Signaling
??????????? Chao Chen and Hongxing Jiang
