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· 제목 : Genetics of Epilepsy and Refractory Epilepsy (Paperback)
· 분류 : 외국도서 > 과학/수학/생태 > 과학 > 생명과학 > 유전학/유전체학
· ISBN : 9781615045327
· 쪽수 : 119쪽
· 출판일 : 2013-03-01
· 분류 : 외국도서 > 과학/수학/생태 > 과학 > 생명과학 > 유전학/유전체학
· ISBN : 9781615045327
· 쪽수 : 119쪽
· 출판일 : 2013-03-01
목차
- Introduction
- What Is Epilepsy?
- Resting Potential
- Action Potential
- Are There Any Genetic Bases for Epilepsy?
- Ligand-gated Ion Channels
- Acetylcholine Receptors CHRNA4, CHRNB2, and CHRNA2
- Ion Channels
- Sodium Channels
- Potassium Channel Subunit Mutations with LOF Effects
- Voltage-gated Calcium Channel Mutations and Genetic Susceptibility
- GABA Receptor Subunit Mutations (Chloride Channel)
- Copy Number Variants and Comorbidities
- Susceptibility Genes for Complex Epilepsy
- Glycine Receptors
- Ionotropic Glutamate Receptors
- G-protein-coupled Receptors
- Metabotropic Glutamate Receptors
- Other Genetic Causes of Epilepsy
- Mitochondrial Inheritance and Myoclonic Epilepsy with Ragged Red Fibers
- Leucine-rich Glioma Inactivated Gene 1 (LGI1)
- Inborn Errors of Metabolism and Epilepsy
- Epilepsy and NMDs
- FOLR1 Gene Mutation
- Lysosomal Storage Disorders
- The Solute-carrier Gene Superfamily and Epilepsy
- Genes Related with Different Epileptic Syndromes
- Genetic Mechanisms of Drug Resistance in Epilepsy
- Definition of Drug Resistance in Epilepsy
- Genetics of Drug Response in Epilepsy
- Drug Transport System
- ABC Transporters
- ABC Transporters and RE
- MDR1 (ABCB1) Gene Variants
- The BBB's Role in Pharmacoresistance in Epilepsy
- Induction of ABC Transporters: Is the Acquired Refractoriness an Inducible Process?
- Genes and Pharmacodynamic Modifications
- Inducing the Expression of P-gp in Neurons: Is it to Induce Epileptogenesis?
- References
- Author Biographies
