알기 쉬운 임상약리학 (이충재 외)

Chapter 01

약리학 총론 Ⅰ 1

Ⅰ. 약리학의 정의 및 학문적 범위· ···········3
Ⅱ. 약력학·································4
1. 약물의 명명·························· 4
2. 약물작용의 분류······················· 5
3. 약물작용과 관련된 일반적 개념············· 7
4. 약물의 작용에 영향을 주는 제반 요소들· ····· 12
Ⅲ. 약동학································19
1. 약물의 생체막 투과···················· 20
2. 약물의 투여경로와 흡수················· 21
3. 약물의 생체내로의 분포················· 23
4. 약물의 대사························· 24
5. 약물의 배설························· 27
6. 임상약동학 영역의 주요 개념· ············ 27
Ⅳ. 조제와 처방····························31
1. 조제······························ 31
2. 처방······························ 33
3. 처방 용어 및 약어····················· 36
4. 의약품의 측정과 환산· ················· 36
Ⅴ. 신약 개발과정에서 임상시험의 의의 및 방법··38
1. 임상시험의 의의······················ 38
2. 임상시험의 방법······················ 38
<학습내용 이해도 평가를 위한 연습문제>· ········ 40

Chapter 02

감염 질환의 치료에 사용되는 약물 Ⅰ 43

Ⅰ. 화학요법과 관련된 기본 개념··············45
1. 항균성 화학요법······················ 45
2. 항균제와 항생제의 정의················· 45
3. 항균범위··························· 45
4. 상협작용과 길항작용··················· 46
Ⅱ. 베타-락탐 항생제 및 다른 세포벽 합성 억제제·46
1. 페니실린류 약물······················ 46
2. 세팔로스포린류 약물··················· 50
3. 기타 β-Lactam 제제· ················· 52
4. 기타 세포벽 합성 억제제· ··············· 53
Ⅲ. Chloramphenicol, Tetracyclines, Macrolides, Clindamycin, Streptogramins and Linezolid· ························54
1. 클로람페니콜류 약물··················· 54
2. 테트라사이클린류 약물· ················ 55
3. 마크로라이드류 약물··················· 57
4. 린코사마이드류 약물··················· 58
5. 스트렙토그라민류 약물· ················ 59
6. 옥사졸리디논류 약물··················· 60
Ⅳ. 아미노당화물계 약물 및 Spectinomycin·····60
Ⅴ. Sulfonamide, Trimethoprim 및
Quinolone계 약물······················62
1. 설폰아미드류 약물· ··················· 62
2. 플루오로퀴놀론류 약물· ················ 63
Ⅵ. 항마이코박테리아 약물···················65
1. 결핵 치료제(항결핵제)·················· 65
2. 한센병(나병) 치료제··················· 67
3. 비정형 마이코박테리아 감염증 치료제· ······ 67
Ⅶ. 항진균제· ·····························67
1. 전신 진균감염증 치료제················· 67
2. 표재성 진균 감염을 치료하는 전신투여 약물· ·· 69
3. 표재성 진균 감염을 치료하는 국소 투여 약물· · 69
Ⅷ. 항바이러스제···························70
1. 단순포진바이러스 치료제················ 71
2. AIDS 바이러스 치료제················· 72
3. 항 HIV 약물: 비 뉴클레오사이드 역전사효소 억제제· 73
4. 항 HIV 약물: HIV-1 단백질 분해효소 억제제··· 74
5. 항 HIV 약물: 진입 억제제················ 74
6. 항인플루엔자 약물· ··················· 75
7. 항간염 약물························· 75
8. 국소적용 항바이러스제· ················ 76
Ⅸ. 기타 항균제 및 소독제, 방부제, 멸균제· ·····76
1. 기타 항균제························· 76
2. 소독제, 방부제, 멸균제················· 78
Ⅹ. 항원충제· ·····························80
1. 아메바 감염증 치료제· ················· 80
2. 폐포자충증 및 톡소플라즈마 감염증 치료제· ··· 81
3. 트리파노소마 감염증 치료제·············· 82
4. 라이슈마니아 감염증 치료제·············· 82
5. 트리코모나스 감염증 치료제·············· 82
6. 말라리아 원충 감염증 치료제(항말라리아제)··· 83
XI. 항윤충제(구충제)························85
1. 선충 구제약························· 86
2. 흡충 구제약························· 87
3. 조충(촌충) 구제약····················· 87
<학습내용 이해도 평가를 위한 연습문제>· ········ 88