Essentials of Functional MRI (Paperback)

IntroductionBasic ConceptsBasic Anatomy of an MRI SystemRepresenting Images with Numbers and Vice VersaRecurring Math Concepts: Representing Data as Sums of Meaningful ComponentsSource of the MR Signal and Its PropertiesOrigins of the MR Signal.The Equilibrium State?Magnetization in Tissues Behavior of the Magnetization When Not at Equilibrium. Pushing the Magnetization Away from Equilibrium?The RF Pulse Detecting the MR Signal. Relaxation Back to Equilibrium Observing the Effects of Relaxation The Fundamental Building Blocks of MRI Methods: Spin Echoes and Gradient EchoesThe Need for EchoesSpin Echo Gradient Echo. Steady-State Methods and Stimulated Echoes. Steady-State Methods Stimulated Echoes. Signal Weighting and ContrastInversion-Recovery MethodsMagnetization Transfer ContrastSummaryCreating an Image from the Magnetic Resonance SignalSpatially Selective Radio-Frequency Pulses Encoding Spatial Information into the MR Signal to Create an ImageConstructing an Image from k-Space Signal Strength, Imaging Speed, and Spatial Resolution?You Cannot Have It All Fast Imaging Methods Parallel Imaging Causes of Image Artifacts and Distortion Principles and Practice of Functional MRIHow MRI Becomes Functional MRIContrast Mechanisms: Linking the MR Signal and Neural FunctionGeneral BOLD fMRI Methods Special Regions.Specific Examples of fMRI Applications?Setting the Acquisition Parameters Alternative Contrast Mechanisms Functional MRI Study DesignBasic Principles of fMRI Study DesignChoice of Stimulation Method or TaskChoice of the fMRI Study DesignOrder and Timing of Presentation of Tasks or StimuliTiming of Tasks or Stimuli, Duration, Sampling Rate.Summary of Factors Influencing fMRI Study DesignFunctional MRI Data AnalysisHypothesis TestingfMRI Analysis Software.PreprocessingData Analysis MethodsStatistical Threshold, and Correction for Multiple ComparisonsGroup Analysis Interpretation of fMRI Results?What Do They Really Mean? Clinical Applications of Functional MRIExamples of Current Clinical Applications of fMRI.Examples of Forthcoming Clinical Applications