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· 분류 : 외국도서 > 과학/수학/생태 > 과학 > 생명과학 > 생화학
· ISBN : 9781461451068
· 쪽수 : 276쪽
· 출판일 : 2012-12-07
목차
Preface.- The GW body Story as an Example of Autoantibodies with Significant Impacts to Molecular Cell Biology.- The Discovery of GW Bodies.- The Discovery and Analysis of P Bodies.- Autoantibodies to Argonaute 2 (Su antigen).- GW/P Bodies and Autoimmune Disease.- Function of GW182 and GW Bodies in siRNA and miRNA Pathways.- Post-Transcriptional Stimulation of Gene Expression by MicroRNAs.- Gawky (Gw) is the Drosophila Melanogaster GW182 Homologue.- The Role of GW182 Proteins in miRNA-mediated Gene Silencing.- Quantifying Argonaute Proteins in and out of GW/P-bodies: Implications in microRNA Activities.- Deadenylation and P-bodies.- Relationship of GW/P-bodies with Stress Granules.- Relationship of other Cytoplasmic Ribonucleoprotein (RNP) Bodies to GW/P Bodies.- A SNP in the Trinucleotide Repeat Region of the TNRC6A Gene Maps to a Major TNGW1 Autoepitope in Patients with Autoantibodies to GW182.- Reflections on Ten Years of History of, and Future Prospects for, GW182 and GW/P Body Research.- Index.