Omics in Clinical Practice: Genomics, Pharmacogenomics, Proteomics, and Transcriptomics in Clinical Research (Hardcover)

Introduction

Part 1: Omics and Human Disease

Comparative Mitochondrial Proteomics: Perspective in Human Diseases; Yujie Jiang and Xin Wang

Studies of Complex Biological Systems with Applications to Molecular Medicine: The Need to Integrate Transcriptomic and Proteomic Approaches; Elena Silvestri, Assunta Lombardi, Pieter de Lange, Daniela Glinni, Rosalba Senese, Federica Cioffi, Antonia Lanni, Fernando Goglia, and Maria Moreno

Next Generation Sequencing in Cancer Research and Clinical Application; Derek Shyr and Qi Liu

Scientific Challenges and Implementation Barriers to Translation of Pharmacogenomics in Clinical Practice; Y. W. Francis Lam

Clinical Proteomics and Omics Clues Useful in Translational Medicine Research; Elena Lopez, Luis Madero, Juan Lopez-Pascual, and Martin Latterich

Genomes2Drugs: Identifies Target Proteins and Lead Drugs from Proteome Data; David Toomey, Heinrich C. Hoppe, Marian P. Brennan, Kevin B. Nolan, and Anthony J. Chubb

Pitfalls and Limitations in Translation from Biomarker Discovery to Clinical Utility in Predictive and Personalised Medicine; Elisabeth Drucker and Kurt Krapfenbauer

How Bioinformatics Influences Health Informatics: Usage of Biomolecular Sequences, Expression Profiles and Automated Microscopic Image Analyses for Clinical Needs and Public Health; Vladimir Kuznetsov, Hwee Kuan Lee, Sebastian Maurer-Stroh, Maria Judit Molnar, Sandor Pongor, Birgit Eisenhaber, and Frank Eisenhaber

Application of "Omics" to Prion Biomarker Discovery; Rhiannon L. C. H. Huzarewich, Christine G. Siemens, and Stephanie A. Booth

Part 4: Omics and Pathogens

Insights from Genomics into Bacterial Pathogen Populations; Daniel J. Wilson

High Throughput Sequencing and Proteomics to Identify Immunogenic Proteins of a New Pathogen: The Dirty Genome Approach; Gilbert Greub, Carole Kebbi-Beghdadi, Claire Bertelli, Francois Collyn, Beat M. Riederer, Camille Yersin, Antony Croxatto, and Didier Raoult

Coronavirus Genomics and Bioinformatics Analysis; Patrick C. Y. Woo, Yi Huang, Susanna K. P. Lau, and Kwok-Yung Yuen

Applications of Next-Generation Sequencing Technologies to Diagnostic Virology; Luisa Barzon, Enrico Lavezzo, Valentina Militello, Stefano Toppo, and Giorgio Palu

Mass Spectrometry-Based Proteomics in Molecular Diagnostics: Discovery of Cancer Biomarkers Using Tissue Culture; Debasish Paul, Avinash Kumar, Akshada Gajbhiye, Manas K. Santra, and Rapole Srikanth

Index